Over the last three years in the Amacher lab, I have been fortunate to work on two amazing projects studying protein-peptide interactions: PDZ domains and Class A sortases. Both recognize a certain substrate motif, and we are interested in these proteins\u27 selectivity and promiscuity of their substrate
Many protein-protein interactions, especially those involved in eukaryotic signalling, are mediated ...
International audienceBACKGROUND: Proteins may evolve through the recruitment and modification of di...
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling...
Many crucial cellular processes are regulated by signaling and trafficking pathways, which are large...
Choanoflagellates are single-celled eukaryotes with complex signaling pathways. They are considered ...
Our research group is broadly interested in peptide-binding domains and how only a small number of a...
Our research group is broadly interested in peptide-binding domains and how only a small number of a...
PDZ domains are protein–protein interaction modules widely used to assemble membranous signaling com...
The PDZ domain family is one of the most abundant peptide recognition modules in metazoan proteomes....
The PDZ domain family is one of the most abundant peptide recognition modules in metazoan proteomes....
Protein-protein interactions are of vital importance to the cell as they mediate the assembly of pro...
Protein-protein interactions are of vital importance to the cell as they mediate the assembly of pro...
Abstract Background PDZ domains are structural protei...
Abstract Background PDZ domains are structural protei...
Many protein-protein interactions, especially those involved in eukaryotic signalling, are mediated ...
Many protein-protein interactions, especially those involved in eukaryotic signalling, are mediated ...
International audienceBACKGROUND: Proteins may evolve through the recruitment and modification of di...
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling...
Many crucial cellular processes are regulated by signaling and trafficking pathways, which are large...
Choanoflagellates are single-celled eukaryotes with complex signaling pathways. They are considered ...
Our research group is broadly interested in peptide-binding domains and how only a small number of a...
Our research group is broadly interested in peptide-binding domains and how only a small number of a...
PDZ domains are protein–protein interaction modules widely used to assemble membranous signaling com...
The PDZ domain family is one of the most abundant peptide recognition modules in metazoan proteomes....
The PDZ domain family is one of the most abundant peptide recognition modules in metazoan proteomes....
Protein-protein interactions are of vital importance to the cell as they mediate the assembly of pro...
Protein-protein interactions are of vital importance to the cell as they mediate the assembly of pro...
Abstract Background PDZ domains are structural protei...
Abstract Background PDZ domains are structural protei...
Many protein-protein interactions, especially those involved in eukaryotic signalling, are mediated ...
Many protein-protein interactions, especially those involved in eukaryotic signalling, are mediated ...
International audienceBACKGROUND: Proteins may evolve through the recruitment and modification of di...
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling...