Linkage analysis of LDL cholesterol in American Indian populations: the Strong Heart Family Study
- North, K. E.
- Göring, H. H.H.
- Cole, S. A.
- Diego, V. P.
- Almasy, L.
- Laston, S.
- Cantu, T.
- Howard, B. V.
- Lee, E. T.
- Best, L. G.
- Fabsitz, R. R.
- MacCluer, J. W.
Publication date
January 2006
DOIAbstract
Previous studies have demonstrated that low density lipoprotein cholesterol (LDL-C) concentration is influenced by both genes and environment. Although rare genetic variants associated with Mendelian causes of increased LDL-C are known, only one common genetic variant has been identified, the apolipoprotein E gene
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