Metabolic insult results in apoptosis and depletion of mature oligodendrocytes during demyelination. To examine the role of insulin-like growth factor-1 (IGF-1) during acute demyelination and remyelination in the adult CNS, we exposed transgenic mice that continuously express IGF-1
The adult mammalian brain contains multiple populations of endogenous progenitor cell types. However...
Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system (CNS)...
To study the effects and mechanisms of insulin-like growth factor I (IGF-I) on brain myelination in ...
Metabolic insult results in apoptosis and depletion of mature oligodendrocytes during demyelination....
In the central nervous system (CNS), insulin-like growth factor 1 (IGF-1) regulates myelination by o...
In the central nervous system (CNS), insulin-like growth factor 1 (IGF-1) regulates myelination by o...
Insulin-like growth factor-I (IGF-I) has been shown to be a potent agent in promoting the growth and...
Our laboratories have reported that TNF-α causes myelin damage and apoptosis of oligodendrocytes and...
To understand mechanisms that may underlie the progression of a demyelinated lesion to a chronic sta...
Repair in multiple sclerosis involves remyelination, a process in which axons are provided with a ne...
Repair in multiple sclerosis involves remyelination, a process in which axons are provided with a ne...
Repair in multiple sclerosis involves remyelination, a process in which axons are provided with a ne...
Insulin-like growth factor-I (IGF-I) has been shown to be a potent agent in promoting the growth and...
Interleukin-1β (IL-1β) is a proinflammatory cytokine associated with the pathophysiology of demyelin...
Three different transgenic mouse models were used to examine the role of Insulin-like growth factor ...
The adult mammalian brain contains multiple populations of endogenous progenitor cell types. However...
Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system (CNS)...
To study the effects and mechanisms of insulin-like growth factor I (IGF-I) on brain myelination in ...
Metabolic insult results in apoptosis and depletion of mature oligodendrocytes during demyelination....
In the central nervous system (CNS), insulin-like growth factor 1 (IGF-1) regulates myelination by o...
In the central nervous system (CNS), insulin-like growth factor 1 (IGF-1) regulates myelination by o...
Insulin-like growth factor-I (IGF-I) has been shown to be a potent agent in promoting the growth and...
Our laboratories have reported that TNF-α causes myelin damage and apoptosis of oligodendrocytes and...
To understand mechanisms that may underlie the progression of a demyelinated lesion to a chronic sta...
Repair in multiple sclerosis involves remyelination, a process in which axons are provided with a ne...
Repair in multiple sclerosis involves remyelination, a process in which axons are provided with a ne...
Repair in multiple sclerosis involves remyelination, a process in which axons are provided with a ne...
Insulin-like growth factor-I (IGF-I) has been shown to be a potent agent in promoting the growth and...
Interleukin-1β (IL-1β) is a proinflammatory cytokine associated with the pathophysiology of demyelin...
Three different transgenic mouse models were used to examine the role of Insulin-like growth factor ...
The adult mammalian brain contains multiple populations of endogenous progenitor cell types. However...
Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system (CNS)...
To study the effects and mechanisms of insulin-like growth factor I (IGF-I) on brain myelination in ...