EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features
- Yamashita, Taro
- Ji, Junfang
- Budhu, Anuradha
- Forgues, Marshonna
- Yang, Wen
- Wang, Hong Yang
- Jia, Huliang
- Ye, Qinghai
- Qin, Lun Xiu
- Wauthier, Elaine
- Reid, Lola M.
- Minato, Hiroshi
- Honda, Masao
- Kaneko, Shuichi
- Tang, Zhao You
- Wang, Xin Wei
Publication date
January 2009
DOIAbstract
Cancer progression/metastases and embryonic development share many properties including cellular plasticity, dynamic cell motility, and integral interaction with the microenvironment. We hypothesized that the heterogeneous nature of hepatocellular carcinoma (HCC) may be, in part, due to the presence of hepatic cancer cells with stem/progenitor features
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