Clinical assessments and microbiology by year of admission.

Clinical assessments (Fig 1A) are summarised using boxplots, with outliers indicated with circles or asterisks for those outside the box by 1.5- or 3-times the interquartile range, respectively. Microbiology is summarised as the total proportion of the cohort that were culture positive (Fig 1B), and the distribution of culture isolates from these positive cases (Fig 1C); unlabelled bars consist of Table 4.