In rodents, intracolonic administration of ethanol 30% induces an acute colitis, while administration of 2,4,6-trinitrobenzene sulphonic acid (TNBS) in ethanol induces a longer lasting colitis. In the acute and chronic stages of experimental colitis, lymphoid and non-lymphoid cells were studied in the colon by immunohistochemistry. During the acute inflammation a high damage score of the colon was observed, which was related to an increase in the number of macrophages and granulocytes. Also a change in distributional patterns of macrophage subpopulations was found. The chronic stage of TNBS-ethanol-induced colitis was characterized by an increase in the number of lymphocytes, especially T cells. These data suggest that macrophages and granu...
To study the proinflammatory and anti-inflammatory cytokines present in the acute phase of trinitrob...
In order to clarify the etiology of inflammatory bowel diseases, some experimental animal models hav...
Rectal instillation of trinitrobenzene sulphonic acid (TNBS) in ethanol is an established model for ...
Epidemiological data suggest an increase in both developed and undeveloped countries of inflammatory...
Epidemiological data suggest an increase in both devel-oped and undeveloped countries of inflammator...
Background: Inflammatory bowel disease (IBD) is a world healthcare problem. In order to evaluate the...
Objective and design: To investigate the severity and duration of colitis induced by two different ...
The gut mucosa is a major site of contact with antigens from food and microbiota. Usually, these dai...
Oral administration of DSS has been reported to induce an acute and chronic colitis in mice. The aim...
The objective of this study was to evaluate the changes in some bacterial species of colonic microbi...
In previous studies we showed that a chronic colitis associated with a Th1 T cell response can be in...
textabstractThe object of this study was to establish whether different pro- and anti-inflammatory m...
The objective of this study was to evaluate the changes in some bacterial species of colonic microbi...
<p><b>(A)</b> Body weight changes (%) of BALB/c mice during four days after the intrarectal instilla...
BACKGROUND Deregulation of the immune response to microbiota or pathogens, and increased intestinal ...
To study the proinflammatory and anti-inflammatory cytokines present in the acute phase of trinitrob...
In order to clarify the etiology of inflammatory bowel diseases, some experimental animal models hav...
Rectal instillation of trinitrobenzene sulphonic acid (TNBS) in ethanol is an established model for ...
Epidemiological data suggest an increase in both developed and undeveloped countries of inflammatory...
Epidemiological data suggest an increase in both devel-oped and undeveloped countries of inflammator...
Background: Inflammatory bowel disease (IBD) is a world healthcare problem. In order to evaluate the...
Objective and design: To investigate the severity and duration of colitis induced by two different ...
The gut mucosa is a major site of contact with antigens from food and microbiota. Usually, these dai...
Oral administration of DSS has been reported to induce an acute and chronic colitis in mice. The aim...
The objective of this study was to evaluate the changes in some bacterial species of colonic microbi...
In previous studies we showed that a chronic colitis associated with a Th1 T cell response can be in...
textabstractThe object of this study was to establish whether different pro- and anti-inflammatory m...
The objective of this study was to evaluate the changes in some bacterial species of colonic microbi...
<p><b>(A)</b> Body weight changes (%) of BALB/c mice during four days after the intrarectal instilla...
BACKGROUND Deregulation of the immune response to microbiota or pathogens, and increased intestinal ...
To study the proinflammatory and anti-inflammatory cytokines present in the acute phase of trinitrob...
In order to clarify the etiology of inflammatory bowel diseases, some experimental animal models hav...
Rectal instillation of trinitrobenzene sulphonic acid (TNBS) in ethanol is an established model for ...