Health-related quality of life in Dutch adult survivors of childhood cancer: A nation-wide cohort study
- van Erp, L. M. E.
- Maurice-Stam, H.
- Kremer, L. C. M.
- Tissing, W. J. E.
- van der Pal, H. J. H.
- de Vries, A. C. H.
- van den Heuvel-Eibrink, M. M.
- Versluys, B. A. B.
- Loonen, J. J.
- Bresters, D.
- Louwerens, M.
- van der Heiden-van der Loo, M.
- van den Berg, M. H.
- Ronckers, C. M.
- van der Kooi, A. L. L. F.
- van Gorp, M.
- van Dulmen-den Broeder, E.
- Grootenhuis, M. A.
DOIAbstract
Aim: To investigate the health-related quality of life (HRQOL) of Dutch adult childhood cancer survivors (CCS) and to identify risk factors of impaired HRQOL. Methods: Adult CCS (age >18, diagnosed <18, ≥5 years since diagnosis) from the Dutch LATER registry completed the Medical Outcome Study Short Form 36 (SF-36) to measure HRQOL and provided sociodemographic characteristics. Age-adjusted mean SF-36 scale scores of CCS were compared to the Dutch general population for men and women separately using t-tests, with effect size d. Multivariate logistic regression models were built to identify sociodemographic and cancer-related risk factors for impaired physical and mental HRQOL. Results: Both male and female CCS (N = 2301, mean age = 35.4 ye...
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