Superposition of PilB<sub>12-163</sub>-PilZ and PilZ-FimX<sub>EAL</sub> structures.
- Edgar E. Llontop (7252868)
- William Cenens (282027)
- Denize C. Favaro (1975516)
- Germán G. Sgro (6716702)
- Roberto K. Salinas (221476)
- Cristiane R. Guzzo (11278921)
- Chuck S. Farah (6716723)
Publication date
August 2021
DOI Publisher
Public Library of Science (PLoS)Abstract
A)Left: Cartoon representations of the PilZ-FimXEAL-c-di-GMP (FimXEAL colored in blue, PilZ colored in orange and c-di-GMP (stick model) colored in red) and PilB12-163-PilZ (PilB12-163 colored in green and PilZ colored in yellow) complexes. Right: Superposition of PilB12-163-PilZ and PilZ-FimXEAL complexes using PilZ as reference. B) Structural alignment of the PilZ structures from A showing the common interface residues in both complexes as sticks. Note that in this figure, the interaction interface (interface 1) between FimXEAL and PilZ is as described previously[24]. An alternative mode of interaction (interface 2) is proposed and tested as described in the main text and detailed in Figs S6, 2F and 4. (TIF)</p
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