Add to ORKGStudy in the field of genetics has identified long non-coding RNA (lncRNA) as a novel class of molecule that participates in cell function in diverse and convoluted ways. The mouse gene U90926 is thought to produce one such lncRNA molecule in activated macrophage cells. Macrophage activation is a key component of the inflammatory response, and is known to influence the onset of autoimmune disorders. My project investigates the protein-coding potential of U90926. Characterization of the molecule(s) produced by this gene will indicate its mechanistic role in regulating macrophage activation. Improved understanding of how this process influences the larger immune response could prompt innovation of new therapies for autoimmune diseases
Infiltrating and resident macrophages are the critical effector cells of the innate immune system, p...
Infiltrating and resident macrophages are the critical effector cells of the innate immune system, p...
There is emerging evidence supporting a role for long non-coding RNAs (lncRNAs) in mediating many fu...
Within healthy individuals, the immune system serves to find and attack foreign substances that have...
Despite increasing evidence to indicate that long non-coding RNAs (lncRNAs) are novel regulators of ...
Long non-coding RNAs (lncRNAs) are a class of non-coding RNA transcripts that have more than 200 nuc...
Emerging studies have identified thousands of long non-coding RNAs (lncRNAs) in mammalian genomes th...
A macrophage is an important component of innate immunity which can be activated by infection. A ser...
Long noncoding RNAs (lncRNAs) are defined as transcripts with more than 200 nucleotides that have li...
© 2017 Roux, Heward, Donnelly, Jones and Lindsay. Despite increasing evidence to indicate that long ...
ABSTRACTNon-Coding RNAs Regulate Innate Immune Signaling Haley Lynne Halasz As our understanding of ...
Despite increasing evidence to indicate that long non-coding RNAs (lncRNAs) are novel regulators of ...
Contemporary genetic research has found that gene expression often takes place by a diverse array of...
The innate immune system provides a first line of defense against pathogens by initiating a protecti...
The innate immune system provides a first line of defense against pathogens by initiating a protecti...
Infiltrating and resident macrophages are the critical effector cells of the innate immune system, p...
Infiltrating and resident macrophages are the critical effector cells of the innate immune system, p...
There is emerging evidence supporting a role for long non-coding RNAs (lncRNAs) in mediating many fu...
Within healthy individuals, the immune system serves to find and attack foreign substances that have...
Despite increasing evidence to indicate that long non-coding RNAs (lncRNAs) are novel regulators of ...
Long non-coding RNAs (lncRNAs) are a class of non-coding RNA transcripts that have more than 200 nuc...
Emerging studies have identified thousands of long non-coding RNAs (lncRNAs) in mammalian genomes th...
A macrophage is an important component of innate immunity which can be activated by infection. A ser...
Long noncoding RNAs (lncRNAs) are defined as transcripts with more than 200 nucleotides that have li...
© 2017 Roux, Heward, Donnelly, Jones and Lindsay. Despite increasing evidence to indicate that long ...
ABSTRACTNon-Coding RNAs Regulate Innate Immune Signaling Haley Lynne Halasz As our understanding of ...
Despite increasing evidence to indicate that long non-coding RNAs (lncRNAs) are novel regulators of ...
Contemporary genetic research has found that gene expression often takes place by a diverse array of...
The innate immune system provides a first line of defense against pathogens by initiating a protecti...
The innate immune system provides a first line of defense against pathogens by initiating a protecti...
Infiltrating and resident macrophages are the critical effector cells of the innate immune system, p...
Infiltrating and resident macrophages are the critical effector cells of the innate immune system, p...
There is emerging evidence supporting a role for long non-coding RNAs (lncRNAs) in mediating many fu...