Background The diagnosis of antibody-mediated rejection (AMR) is reached using the Banff Classification for Allograft Pathology, which now includes gene expression analysis. In this study, we investigate the application of “Increased Expression Of Thoroughly Validated Gene Transcripts/Classifiers Strongly Associated With AMR” as a diagnostic criteria. Method We used qRT-PCR for 10 genes associated with AMR in a retrospective cohort of 297 transplant biopsies, including biopsies that met the full diagnostic criteria for AMR, even without molecular data (AMR, n = 27); biopsies that showed features of AMR, but that would only meet criteria for AMR with increased transcripts (AMRsusp, n = 49) and biopsies that would never meet criteria for AMR ...
Transcriptomics could contribute significantly to the early and specific diagnosis of rejection epis...
Background Whole genome microarray meta-analyses of 1030 kidney, heart, lung and liver allograft bio...
Abstract Background: Development of noninvasive molecular assays to improve disease diagnosis and pa...
Introduction Microarray studies have shown elevated transcript levels of endothelial and natural kil...
Introduction: Peripheral blood (PB) molecular patterns characterizing the different effector immune ...
Rejection-associated gene expression has been characterized in renal allograft biopsies for cause. T...
Rejection-associated gene expression has been characterized in renal allograft biopsies for cause. T...
Introduction Immunohistochemical staining for C4d in peritubular capillaries has been part of antibo...
AbstractAffymetrix Human Gene 1.0-ST arrays were used to assess the gene expression profiles of kidn...
Introduction: Immunohistochemical staining for C4d in peritubular capillaries has been part of antib...
Background\ud \ud Development of noninvasive molecular assays to improve disease diagnosis and patie...
BACKGROUND: In kidney transplant recipients, surveillance biopsies can reveal, despite stable graft ...
Background: Acute T-cell mediated rejection (TCMR) is usually indicated by alteration in serum-creat...
To test, whether 10 genes, diagnostic of renal allograft rejection in blood, are able to diagnose an...
Background: There is an urgent need to develop and implement low cost, high-throughput standardized ...
Transcriptomics could contribute significantly to the early and specific diagnosis of rejection epis...
Background Whole genome microarray meta-analyses of 1030 kidney, heart, lung and liver allograft bio...
Abstract Background: Development of noninvasive molecular assays to improve disease diagnosis and pa...
Introduction Microarray studies have shown elevated transcript levels of endothelial and natural kil...
Introduction: Peripheral blood (PB) molecular patterns characterizing the different effector immune ...
Rejection-associated gene expression has been characterized in renal allograft biopsies for cause. T...
Rejection-associated gene expression has been characterized in renal allograft biopsies for cause. T...
Introduction Immunohistochemical staining for C4d in peritubular capillaries has been part of antibo...
AbstractAffymetrix Human Gene 1.0-ST arrays were used to assess the gene expression profiles of kidn...
Introduction: Immunohistochemical staining for C4d in peritubular capillaries has been part of antib...
Background\ud \ud Development of noninvasive molecular assays to improve disease diagnosis and patie...
BACKGROUND: In kidney transplant recipients, surveillance biopsies can reveal, despite stable graft ...
Background: Acute T-cell mediated rejection (TCMR) is usually indicated by alteration in serum-creat...
To test, whether 10 genes, diagnostic of renal allograft rejection in blood, are able to diagnose an...
Background: There is an urgent need to develop and implement low cost, high-throughput standardized ...
Transcriptomics could contribute significantly to the early and specific diagnosis of rejection epis...
Background Whole genome microarray meta-analyses of 1030 kidney, heart, lung and liver allograft bio...
Abstract Background: Development of noninvasive molecular assays to improve disease diagnosis and pa...