Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) significantly, there are still a large proportion of ccRCC patients who progress to metastasis. Targeting the pro-metastatic immune cell in the ccRCC microenvironment could provide a solution to this problem. In this study, B cells in ccRCC biopsies were identified by using scRNA-seq and flow cytometry. The findings indicated the presence of a pro-metastatic B cell type which could be further classified into 3 subpopulations, MARCH3, B2M and DTWD1, based on their large-scaled genetic profiles, rather than traditional Immature/Mature ones. Although all of the 3 subpopulations appeared to contribute to distant metastasis, B cell (B2M) was deemed to be...
Clear cell renal cell carcinoma (ccRCC) has a high metastatic rate, and its incidence and mortality ...
Purpose: The determination of prognosis in patients with renal cell carcinoma (RCC) is based, classi...
Background: Renal cell carcinoma (RCC) is one of the most common cancers, with an annual incidence o...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and metabolic he...
Immune cells within the tumor microenvironment (TME) play a critical role in regulating tumor develo...
Clear-cell renal cell carcinoma (ccRCC) is a common therapy resistant disease with aberrant angiogen...
Clear cell renal cell carcinoma (ccRCC) has a high metastatic rate, and its incidence and mortality ...
Purpose: The determination of prognosis in patients with renal cell carcinoma (RCC) is based, classi...
Background: Renal cell carcinoma (RCC) is one of the most common cancers, with an annual incidence o...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) signifi...
Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and metabolic he...
Immune cells within the tumor microenvironment (TME) play a critical role in regulating tumor develo...
Clear-cell renal cell carcinoma (ccRCC) is a common therapy resistant disease with aberrant angiogen...
Clear cell renal cell carcinoma (ccRCC) has a high metastatic rate, and its incidence and mortality ...
Purpose: The determination of prognosis in patients with renal cell carcinoma (RCC) is based, classi...
Background: Renal cell carcinoma (RCC) is one of the most common cancers, with an annual incidence o...