Protocol schema for tumor-bearing companion dogs receiving external beam radiation therapy in combination with intratumoral hu14.18-IL2 immunocytokine.

Small animal image-guided radiotherapy: status, considerations and potential for translational impact

Butterworth, K. T.
Prise, K. M.
Verhaegen, F.

January 2015

Radiation biology is being transformed by the implementation of small animal image-guided precision ...

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.

Melissa Paoloni
Christina Mazcko
Kimberly Selting
Susan Lana
Lisa Barber
Jeffrey Phillips
Katherine Skorupski
David Vail
Heather Wilson
Barbara Biller
Anne Avery
Matti Kiupel
Amy LeBlanc
Anna Bernhardt
Beatrice Brunkhorst
Robert Tighe
Chand Khanna

Interleukin (IL)-12 is a pro-inflammatory cytokine that mediates T-helper type 1 responses and cytot...

Radioimmunotherapy Targeting IGF2R on Canine-Patient-Derived Osteosarcoma Tumors in Mice and Radiation Dosimetry in Canine and Pediatric Models

Jaline Broqueza
Chandra B. Prabaharan
Kevin J. H. Allen
Rubin Jiao
Darrell R. Fisher
Ryan Dickinson
Valerie MacDonald-Dickinson
Maruti Uppalapati
Ekaterina Dadachova

December 2021

Background: Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant impro...

Protocol schema for tumor-bearing companion dogs receiving external beam radiation therapy in combination with intratumoral hu14.18-IL2 immunocytokine and 86/90Y-NM600 targeted radionuclide therapy.

Kara Magee (11268683)
Ian R. Marsh (3041166)
Michelle M. Turek (11268686)
Joseph Grudzinski (11268689)
Eduardo Aluicio-Sarduy (1610008)
Jonathan W. Engle (325235)
Ilene D. Kurzman (11268692)
Cindy L. Zuleger (11268695)
Elizabeth A. Oseid (11268698)
Christine Jaskowiak (11268701)
Mark R. Albertini (11268704)
Karla Esbona (3580781)
Bryan Bednarz (11268707)
Paul M. Sondel (5408369)
Jamey P. Weichert (400808)
Zachary S. Morris (6287090)
Reinier Hernandez (1329030)
David M. Vail (11268710)

August 2021

Protocol schema for tumor-bearing companion dogs receiving external beam radiation therapy in combin...

Target-Based Radiosensitization Strategies: Concepts and Companion Animal Model Outlook

Matthew R. Berry
Timothy M. Fan
Timothy M. Fan

October 2021

External beam radiotherapy is indicated in approximately 50-60% of human cancer patients. The prescr...

Clinical characteristics of companion animals treated with 3D printed bolus during radiation therapy.

Eric Ehler (5807543)
David Sterling (699600)
Kathryn Dusenbery (5807546)
Jessica Lawrence (849961)

October 2018

Clinical characteristics of companion animals treated with 3D printed bolus during radiation therapy...

Emerging Translational Opportunities in Comparative Oncology With Companion Canine Cancers: Radiation Oncology.

Nolan, Michael W
Kent, Michael S
Boss, Mary-Keara

January 2019

It is estimated that more than 6 million pet dogs are diagnosed with cancer annually in the USA. Bot...

Surgical Veterinary Oncology, is the companion animal truly a good spontaneous model for human disease?

Kirpensteijn, J.

October 2009

Prof. Jolle Kirpensteijn, DVM, of the Faculty of Veterinary Medicine’s Department of Clinical Scienc...

Tumor response assessment in veterinary medicine and RECIST criteria

Grotens, T.S.

October 2009

In human and veterinary medicine, cancer remains a major health problem, and the overall incidence o...

How companion animals contribute to the fight against cancer in humans

Douglas Thamm, VMD
Steven Dow, DVM, PhD

March 2009

Companion animals and their human guardians suffer from many of the same types of cancer and are oft...

Radiotherapy in the management of localized mucocutaneous oral lymphoma in dogs: 14 cases.

BERLATO, DAVIDE
Schrempp D.
Van Den Steen N.
Murphy S.

January 2012

Oral mucocutaneous lymphoma is rare in dogs. Surgery and chemotherapy do not usually provide effecti...

SAFETY AND TOXICITY OF AN ACCELERATED COARSELY FRACTIONATED RADIATION PROTOCOL FOR TREATMENT OF APPENDICULAR OSTEOSARCOMA IN 14 DOGS: 10 GY × 2 FRACTIONS

Pagano, Candace
Boudreaux, Bonnie
Shiomitsu, Keijiro

September 2016

Coarsely fractionated radiation is commonly used as a method for pain control in dogs with appendicu...

Exploring the Potential Utility of Pet Dogs With Cancer for Studying Radiation-Induced Immunogenic Cell Death Strategies

Timothy M. Fan
Kimberly A. Selting

January 2019

Radiotherapy serves as a foundational pillar for the therapeutic management of diverse solid tumors ...

Schema representing the schedule for the dose escalation phase of RGD-A-TNF evaluation in dogs with spontaneous cancers.

Melissa C. Paoloni (247731)
Anita Tandle (373602)
Christina Mazcko (247733)
Engy Hanna (373603)
Stefan Kachala (373604)
Amy LeBlanc (373605)
Shelley Newman (373606)
David Vail (373607)
Carolyn Henry (373608)
Douglas Thamm (164655)
Karin Sorenmo (373609)
Amin Hajitou (373610)
Renata Pasqualini (502)
Wadih Arap (47813)
Chand Khanna (219274)
Steven K. Libutti (265430)

February 2013

(A) This study was structured as a dose-escalation using a modified Fibonacci design to govern do...

Combined radioimmunotherapy and radiotherapy of human colon carcinoma grafted in nude mice

Buchegger, F.
Rojas, A.
Bischof Delaloye, A.
Vogel, C. A.
Mirimanoff, R. O.
Coucke, P.
Sun, L. Q.
Raimondi, S.
Denekamp, J.
Pelgrin, A.
Delaloye, B.
Mach, JP.

January 1995

The effect of combined radioimmunotherapy (RIT) and fractionated external beam radiotherapy (RT) was...

Small animal image-guided radiotherapy: status, considerations and potential for translational impact

Butterworth, K. T.
Prise, K. M.
Verhaegen, F.

January 2015

Radiation biology is being transformed by the implementation of small animal image-guided precision ...

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.

Melissa Paoloni
Christina Mazcko
Kimberly Selting
Susan Lana
Lisa Barber
Jeffrey Phillips
Katherine Skorupski
David Vail
Heather Wilson
Barbara Biller
Anne Avery
Matti Kiupel
Amy LeBlanc
Anna Bernhardt
Beatrice Brunkhorst
Robert Tighe
Chand Khanna

Interleukin (IL)-12 is a pro-inflammatory cytokine that mediates T-helper type 1 responses and cytot...

Radioimmunotherapy Targeting IGF2R on Canine-Patient-Derived Osteosarcoma Tumors in Mice and Radiation Dosimetry in Canine and Pediatric Models

Jaline Broqueza
Chandra B. Prabaharan
Kevin J. H. Allen
Rubin Jiao
Darrell R. Fisher
Ryan Dickinson
Valerie MacDonald-Dickinson
Maruti Uppalapati
Ekaterina Dadachova

December 2021

Background: Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant impro...

Protocol schema for tumor-bearing companion dogs receiving external beam radiation therapy in combination with intratumoral hu14.18-IL2 immunocytokine and 86/90Y-NM600 targeted radionuclide therapy.

Kara Magee (11268683)
Ian R. Marsh (3041166)
Michelle M. Turek (11268686)
Joseph Grudzinski (11268689)
Eduardo Aluicio-Sarduy (1610008)
Jonathan W. Engle (325235)
Ilene D. Kurzman (11268692)
Cindy L. Zuleger (11268695)
Elizabeth A. Oseid (11268698)
Christine Jaskowiak (11268701)
Mark R. Albertini (11268704)
Karla Esbona (3580781)
Bryan Bednarz (11268707)
Paul M. Sondel (5408369)
Jamey P. Weichert (400808)
Zachary S. Morris (6287090)
Reinier Hernandez (1329030)
David M. Vail (11268710)

August 2021

Protocol schema for tumor-bearing companion dogs receiving external beam radiation therapy in combin...

Target-Based Radiosensitization Strategies: Concepts and Companion Animal Model Outlook

Matthew R. Berry
Timothy M. Fan
Timothy M. Fan

October 2021

External beam radiotherapy is indicated in approximately 50-60% of human cancer patients. The prescr...

Clinical characteristics of companion animals treated with 3D printed bolus during radiation therapy.

Eric Ehler (5807543)
David Sterling (699600)
Kathryn Dusenbery (5807546)
Jessica Lawrence (849961)

October 2018

Clinical characteristics of companion animals treated with 3D printed bolus during radiation therapy...

Emerging Translational Opportunities in Comparative Oncology With Companion Canine Cancers: Radiation Oncology.

Nolan, Michael W
Kent, Michael S
Boss, Mary-Keara

January 2019

It is estimated that more than 6 million pet dogs are diagnosed with cancer annually in the USA. Bot...

Surgical Veterinary Oncology, is the companion animal truly a good spontaneous model for human disease?

Kirpensteijn, J.

October 2009

Prof. Jolle Kirpensteijn, DVM, of the Faculty of Veterinary Medicine’s Department of Clinical Scienc...

Tumor response assessment in veterinary medicine and RECIST criteria

Grotens, T.S.

October 2009

In human and veterinary medicine, cancer remains a major health problem, and the overall incidence o...

How companion animals contribute to the fight against cancer in humans

Douglas Thamm, VMD
Steven Dow, DVM, PhD

March 2009

Companion animals and their human guardians suffer from many of the same types of cancer and are oft...

Radiotherapy in the management of localized mucocutaneous oral lymphoma in dogs: 14 cases.

BERLATO, DAVIDE
Schrempp D.
Van Den Steen N.
Murphy S.

January 2012

Oral mucocutaneous lymphoma is rare in dogs. Surgery and chemotherapy do not usually provide effecti...

SAFETY AND TOXICITY OF AN ACCELERATED COARSELY FRACTIONATED RADIATION PROTOCOL FOR TREATMENT OF APPENDICULAR OSTEOSARCOMA IN 14 DOGS: 10 GY × 2 FRACTIONS

Pagano, Candace
Boudreaux, Bonnie
Shiomitsu, Keijiro

September 2016

Coarsely fractionated radiation is commonly used as a method for pain control in dogs with appendicu...

Exploring the Potential Utility of Pet Dogs With Cancer for Studying Radiation-Induced Immunogenic Cell Death Strategies

Timothy M. Fan
Kimberly A. Selting

January 2019

Radiotherapy serves as a foundational pillar for the therapeutic management of diverse solid tumors ...

Schema representing the schedule for the dose escalation phase of RGD-A-TNF evaluation in dogs with spontaneous cancers.

Melissa C. Paoloni (247731)
Anita Tandle (373602)
Christina Mazcko (247733)
Engy Hanna (373603)
Stefan Kachala (373604)
Amy LeBlanc (373605)
Shelley Newman (373606)
David Vail (373607)
Carolyn Henry (373608)
Douglas Thamm (164655)
Karin Sorenmo (373609)
Amin Hajitou (373610)
Renata Pasqualini (502)
Wadih Arap (47813)
Chand Khanna (219274)
Steven K. Libutti (265430)

February 2013

(A) This study was structured as a dose-escalation using a modified Fibonacci design to govern do...

Combined radioimmunotherapy and radiotherapy of human colon carcinoma grafted in nude mice

Buchegger, F.
Rojas, A.
Bischof Delaloye, A.
Vogel, C. A.
Mirimanoff, R. O.
Coucke, P.
Sun, L. Q.
Raimondi, S.
Denekamp, J.
Pelgrin, A.
Delaloye, B.
Mach, JP.

January 1995

The effect of combined radioimmunotherapy (RIT) and fractionated external beam radiotherapy (RT) was...

Small animal image-guided radiotherapy: status, considerations and potential for translational impact

Butterworth, K. T.
Prise, K. M.
Verhaegen, F.

January 2015

Radiation biology is being transformed by the implementation of small animal image-guided precision ...

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.

Melissa Paoloni
Christina Mazcko
Kimberly Selting
Susan Lana
Lisa Barber
Jeffrey Phillips
Katherine Skorupski
David Vail
Heather Wilson
Barbara Biller
Anne Avery
Matti Kiupel
Amy LeBlanc
Anna Bernhardt
Beatrice Brunkhorst
Robert Tighe
Chand Khanna

Interleukin (IL)-12 is a pro-inflammatory cytokine that mediates T-helper type 1 responses and cytot...

Radioimmunotherapy Targeting IGF2R on Canine-Patient-Derived Osteosarcoma Tumors in Mice and Radiation Dosimetry in Canine and Pediatric Models

Jaline Broqueza
Chandra B. Prabaharan
Kevin J. H. Allen
Rubin Jiao
Darrell R. Fisher
Ryan Dickinson
Valerie MacDonald-Dickinson
Maruti Uppalapati
Ekaterina Dadachova

December 2021

Background: Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant impro...

Protocol schema for tumor-bearing companion dogs receiving external beam radiation therapy in combination with intratumoral hu14.18-IL2 immunocytokine.

Abstract

Extracted data

Protocol schema for tumor-bearing companion dogs receiving external beam radiation therapy in combination with intratumoral hu14.18-IL2 immunocytokine.

Abstract

Extracted data

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