An acute <i>in vivo</i> model of vaping indicates cytotoxicity.
- Rui Zhang (13940)
- Myles M. Jones (11268824)
- De’Jana Parker (11268827)
- Ronna E. Dornsife (11268830)
- Nathan Wymer (11268833)
- Rob U. Onyenwoke (11268836)
- Vijay Sivaraman (466073)
Publication date
August 2021
DOI Publisher
Public Library of Science (PLoS)Abstract
Mice received either PBS, vaped PG/VG vehicle, resting e-liquid or vaped e-liquid (10 μl) once daily intranasal (IN) for 3 days and were then euthanized. n = 4 mice per treatment group. H&E staining (200X magnification) of sections of lung tissue isolated from mock-, vaped vehicle-, resting e-liquid- or vaped e-liquid- treated mice. Alveolar wall thickening was particularly observable in the lungs from the vaped e-liquid-treated mice compared to the mock control. Arrows indicate alveoli thickening and neutrophil influx. (PPTX)</p
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