S7 Fig -

(A) Western blots showing the kinetics of Med16-AID depletion and stability of TBP-3xFLAG-MNase upon 3-IAA treatment of cells. (B) Boxplots of replicate log2 upstream/TESR TBP ChEC-seq signal from Med16-AID cells treated with DMSO or 3-IAA at genes dysregulated by Med16 depletion. (C) Tracks of TBP ChEC-seq signal from cells treated with DMSO or 3-IAA at genes dysregulated by Med16 depletion. (D) Boxplots of average log2 upstream/TESR TBP ChEC-seq signal from Med16-AID cells treated with DMSO or 3-IAA at the given fraction of all genes ranked by nsRNA log2 fold change. (E) Average plots of replicate TBP ChEC-seq signal (≤80 bp fragments) from Med16-AID cells treated with DMSO or 3-IAA at Med16-down genes. (F) Same as (E) but for Med16-up genes. (TIF)