NUP98-HOXA9 collaborates with HTH during <i>Drosophila</i> eye development.

FLP-out clones produced in the eye using ey-FLP; Act5C > CD8 > Gal4, UAS-GFP were analyzed at the adult and larval stages. (A, C, E, G) Micrographs of representative adult Drosophila eyes clonally expressing (A) UAS-LacZ/+, (B) UAS-NA9/+, (C) UAS-GFP-hth, and (D) UAS-NA9/UAS-GFP-hth as indicated to the left of each panel. (B, D, F, H) Third instar eye discs labeled with BrdU revealing cells in S phase. GFP staining marks the positions of clones expressing the transgenes indicated to the left of the panels. Yellow arrowhead indicates the position of the second mitotic wave. (I) Quantification of eye size and tissue overgrowth. Statistical significance was assessed using a Student’s t test.