Results of the AI analysis along with information from microarray-based copy-number analysis (Fig 2), indicated in grey scale. Columns indicate individual tumors. Note that copy-number variations irrelevant to the indicated markers are not shown. aMarkers with (black with asterisk) or without (grey) heterozygous individuals. bNo data present in the rn4 rat genome assembly; values in parentheses are from the Celera assembly. ‘H’, markers exhibiting homozygosity, where allelic analyses were impossible.</p
Human breast tumours were analyzed with polymorphic microsatellite markers specific to chromosome 3p...
Intra-tumor heterogeneity concerns the existence of genetically different subclones within the same ...
Background: Development of breast cancer is a multistage process influenced by hormonal and environm...
A, Chromosomal losses (green) and gains (red) in 21 tumors. Aberrations observed in the same carcino...
<div><p>The study of somatic genetic alterations in tumors contributes to the understanding and mana...
The study of somatic genetic alterations in tumors contributes to the understanding and management o...
Breast cancer is a heterogeneous disease and patients with similar pathologies and treatments may ha...
Somatically-acquired allelic imbalance (AI) is an established factor in cancer initiation and has re...
g.oxfordjournals.org/ D ow nloaded from 1 The contribution of BRCA1 and BRCA2 to familial and non-fa...
Loss of heterozygosity (LOH) and allelic imbalance (AI) at loci reported to show allele loss and/or ...
In this study, 23 low malignant potential (LMP) and 27 invasive epithelial ovarian tumours have been...
Introduction: Human epidermal growth factor receptor 2 (HER2)-amplified breast cancer represents a c...
The analysis of loss of heterozygosity (LOH) in tumours can be used to map candidate sites of tumour...
<p>(A) Representative array-based CGH profiles from two RCC tumors. The red lines show log2 ratios o...
BACKGROUND: Breast cancer is a heterogeneous disease and patients with similar pathologies and treat...
Human breast tumours were analyzed with polymorphic microsatellite markers specific to chromosome 3p...
Intra-tumor heterogeneity concerns the existence of genetically different subclones within the same ...
Background: Development of breast cancer is a multistage process influenced by hormonal and environm...
A, Chromosomal losses (green) and gains (red) in 21 tumors. Aberrations observed in the same carcino...
<div><p>The study of somatic genetic alterations in tumors contributes to the understanding and mana...
The study of somatic genetic alterations in tumors contributes to the understanding and management o...
Breast cancer is a heterogeneous disease and patients with similar pathologies and treatments may ha...
Somatically-acquired allelic imbalance (AI) is an established factor in cancer initiation and has re...
g.oxfordjournals.org/ D ow nloaded from 1 The contribution of BRCA1 and BRCA2 to familial and non-fa...
Loss of heterozygosity (LOH) and allelic imbalance (AI) at loci reported to show allele loss and/or ...
In this study, 23 low malignant potential (LMP) and 27 invasive epithelial ovarian tumours have been...
Introduction: Human epidermal growth factor receptor 2 (HER2)-amplified breast cancer represents a c...
The analysis of loss of heterozygosity (LOH) in tumours can be used to map candidate sites of tumour...
<p>(A) Representative array-based CGH profiles from two RCC tumors. The red lines show log2 ratios o...
BACKGROUND: Breast cancer is a heterogeneous disease and patients with similar pathologies and treat...
Human breast tumours were analyzed with polymorphic microsatellite markers specific to chromosome 3p...
Intra-tumor heterogeneity concerns the existence of genetically different subclones within the same ...
Background: Development of breast cancer is a multistage process influenced by hormonal and environm...