Gastric nodules with Neospora caninum zooites in a confirmed clinical Neospora caninum infection in a dog

Generalized neosporosis was diagnosed in a two year old rottweiler. The dog had a history of tetraparesis, muscle atrophy, regurgitation and vomiting. Serological analysis by indirect fluorescent antibody test was 1/400 for Neospora caninum. Contrasted radiological surveys showed megaesophagus and during ultrasonografic examination an 8.2 mm diameter mural nodule was observed at the pyloric region. Citologic evaluation revealed highly number of zooites. Microscopically, severe myositis were observed in histologic muscle sections and several groups of tachyzoites and tissue cysts were associated with these lesions. The result of the immunhistochemical staining was: protozoa in muscle sections of the dog stained strongly using 5.2.15 monoclonal antibodies against N. caninum tachyzoites. This paper describes a clinical case of canine neosporosis with vomiting associated to Neospora gastric nodule