International audienceDisentangling the relative contribution of the various factors underlying Middle Palaeolithic industrial variability remains one of the foremost problems for researchers interested in Neandertal technological and behavioural adaptations. The site of Combe-Grenal (Dordogne) has figured prominently in these discussions given its long stratigraphic sequence and rich archaeological record that extends from MIS 6 to MIS 3 and contains all of F. Bordes' Mousterian facies. Departing from a strict typological approach, we provide a revised vision of the site's sequence focused on individualising lithic production systems. We investigate to what extent typologically different industries, beyond their separation imposed by the v...