Association of vitamin D with statin induced myalgia

Objective: To determine the association of serum 25-hydroxy vitamin D (25(OH) Vitamin D) deficiency with the occurrence of myalgia in patients on statin therapy. Methods: The pathology laboratory database was reviewed to identify patients tested for serum 25(OH) Vitamin D and creatine kinase. A retrospective chart review was then conducted to ascertain statin use and reporting of myalgia for patients tested concurrently for serum 25(OH) vitamin D and creatinekinase levels between January 1, 2013 and December 31, 2013. Results: Of the 825 patients tested for creatine kinase and 25 (OH) Vitamin D in 2013, 49 met the study criteria.The mean serum 25 (OH) Vitamin D level in the 24 statin induced myalgiapatients was 17.93 ± 12.07 compared to 18.99 ± 15.2 in the 25 no SIM group (p = 0.81). Conclusion: Our study reports no association between statin induced myalgia and low 25 (OH) vitamin D levels