Alzheimer\u27s disease (AD) is a neurodegenerative disorder, which depicts features of chronic inflammatory conditions resulting in cellular death and has limited therapeutic options. We aimed to explore the effect of a curcuminoid mixture and its individual components on inflammatory and apoptotic genes expression in AD using an A beta + ibotenic acid-infused rat model. After 5 days of treatment with demethoxycurcumin, hippocampal IL-1 beta levels were decreased to 118.54 +/- 47.48 and 136.67 +/- 31.96% respectively at 30 and 10 mg/kg, compared with the amyloid treated group (373.99 +/- 15.28%). After 5 days of treatment, the curcuminoid mixture and demethoxycurcumin effectively decreased GFAP levels in the hippocampus. When studied for th...
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging population. Given t...
Curcumin, the most active component of turmeric, has various beneficial properties, such as antioxid...
Curcuminoids (a mixture of curcumin, bisdemethoxycurcumin and demethoxycurcumin) share vital pharmac...
Alzheimer\u27s disease (AD) is a neurodegenerative disorder, which depicts features of chronic infla...
Alzheimer\u27s disease (AD) is a neurodegenerative disease. There are a limited number of therapeuti...
Recently the neuronal toxicity of intracellular amyloid beta (iA beta) in Alzheimer's disease i...
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive cognitive imp...
The multifactorial character of Alzheimer’s disease (AD) represents a significant impediment to achi...
Pamela E Potter Department of Pharmacology, Arizona College of Osteopathic Medicine, Midwestern Univ...
Curcumin is the primary curcuminoid found in the rhizome of the turmeric plant (Curcuma longa), resp...
<div><p>Curcumin, the most active component of turmeric, has various beneficial properties, such as ...
Alzheimer\u27s disease (AD) is the most common form of dementia. There is limited choice in modern t...
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that is associated with the most co...
Curcumin derived from turmeric is well documented for its anti-carcinogenic, antioxidant and anti-in...
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging population. Given t...
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging population. Given t...
Curcumin, the most active component of turmeric, has various beneficial properties, such as antioxid...
Curcuminoids (a mixture of curcumin, bisdemethoxycurcumin and demethoxycurcumin) share vital pharmac...
Alzheimer\u27s disease (AD) is a neurodegenerative disorder, which depicts features of chronic infla...
Alzheimer\u27s disease (AD) is a neurodegenerative disease. There are a limited number of therapeuti...
Recently the neuronal toxicity of intracellular amyloid beta (iA beta) in Alzheimer's disease i...
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive cognitive imp...
The multifactorial character of Alzheimer’s disease (AD) represents a significant impediment to achi...
Pamela E Potter Department of Pharmacology, Arizona College of Osteopathic Medicine, Midwestern Univ...
Curcumin is the primary curcuminoid found in the rhizome of the turmeric plant (Curcuma longa), resp...
<div><p>Curcumin, the most active component of turmeric, has various beneficial properties, such as ...
Alzheimer\u27s disease (AD) is the most common form of dementia. There is limited choice in modern t...
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that is associated with the most co...
Curcumin derived from turmeric is well documented for its anti-carcinogenic, antioxidant and anti-in...
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging population. Given t...
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging population. Given t...
Curcumin, the most active component of turmeric, has various beneficial properties, such as antioxid...
Curcuminoids (a mixture of curcumin, bisdemethoxycurcumin and demethoxycurcumin) share vital pharmac...