Large-scale Centralized Radiopharmacies: Is There Any Reason for Concern? An Insight into 99mTc-radiopharmaceuticals Adsorption and Stability

Worldwide, regulatory issues related to the field of radiopharmacy are switching and turning each day more rigid. Due to these legal constraints and all the related economical consequences, the concept of large-scale radiopharmacies, that label and distribute radiopharmaceuticals in a ready-to-use form, disseminate widely and seem more and more attractive, even in usually less receptive countries. In such a context, issues as the appropriate choice for recipient/methodology (vial or syringe? Multi- or Monodoses?) as well as the adoption of distinct behaviors should be considered relevant. Aim: It is aimed to disseminate the results obtained on a large study performed to evaluate whether there is any correlation between factors as syringe volume, residence time and type of radiopharmaceutical with adsorbed fraction and stabilit