Development of novel ionic liquids based on ampicillin
- Ferraz, Ricardo
- Prudêncio, Cristina
- Branco, Luís
- Marrucho, Isabel
- Araújo, João
- Rebelo, Luís
- Ponte, Manuel Nunes
- Noronha, João Paulo
- Petrovski, Zeljko
Publication date
January 2012
DOI Publisher
Royal Society of Chemistry (RSC) ISSN
2040-2503 Citation count (estimate)
52Abstract
Novel ionic liquids containing ampicillin as an active pharmaceutical ingredient anion were prepared with good yields by using a new, efficient synthetic procedure based on the neutralization of a moderately basic ammonia solution of ampicillin with different organic cation hydroxides. The relevant physical and thermal properties of these novel ionic liquids based on ampicillin were also evaluated
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