Fibrosing Cholestatic Hepatitis C Post-Liver Transplantation: A Case Study

Introduction: Liver Transplantation: Hepatitis C infection is the most common indication for liver transplantation in the US HCV infection of the liver allograft occurs within hours from circulating virions. -Serum RNA levels are observed in the first several weeks. -Acute hepatitis occurs in 2-6 months -Chronic hepatitis occurs in 3-9 months ***Persistence of HCV infection is the rule after transplantation due to immune suppression Chronic recurrent HCV infection post transplantation There are four distinct patterns of recurrent chronic HCV in the liver allograft. -Usual chronic HCV (\u3e70%) -Fibrosing Cholestatic Hepatitis C (5-10%) -Plasma cell-rich HCV -HCV overlapping with rejection or autoimmune hepatiti