Isolation and Characterization of Bacillus anthracis Hfq P

All cellular species of life undergo the same order of transfer of genetic information from DNA template to messenger RNA(mRNA) by transcription followed by translation of mRNA to protein. This apparent simplicity is modified and regulated by other processes that interfere, enhance, and add on to this order. One such example is the regulation of the structure and function of mRNAs by small non-coding RNAs and protein Hfq. To date there has been limited research for the Hfq P, one of two Hfq copies found in Bacillus anthracis and the target of this paper. We hypothesize that the Hfq P is similar in biochemical properties to the E. coli Hfq. If true, further study on this Hfq P may reveal its potential as a target for medicine and treatment.Roger Wartell - Faculty Mentor ; Patricia Sobecky - Committee Member/Second Reade