This thesis deals with the approximation of the expectation of a functional (possibly depending on the whole path) applied to a diffusion process (possibly multidimensional). The motivation for this work comes from financial mathematics where the pricing of options is reduced to the calculation of such expectations. The rapidity for price computations and calibration procedures is a very strong operational constraint and we provide real-time tools (or at least more competitive than Monte Carlo simulations in the case of multidimensional diffusions) to meet these needs. In order to derive approximation formulas, we choose a proxy model in which analytical calculus are possible and then we use stochastic expansions around the proxy model and ...