376 authors, 18 pages, 14 figures, 5 tables. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are publicly available at http://www.phenix.bnl.gov/phenix/WWW/info/data/ppg123_data.htmlBackground: Heavy-flavor production in p+p collisions tests perturbative-quantum-chromodynamics (pQCD) calculations. Modification of heavy-flavor production in heavy-ion collisions relative to binary-collision scaling from p+p results, quantified with the nuclear-modification factor (R_AA), provides information on both cold- and hot-nuclear-matter effects. Purpose: Determine transverse-momentum, pt, spectra and the corresponding R_AA for muons from heavy-flavor mesons decay in p+p and Cu+Cu collisions at sqrt(s_...