4NQO Carcinogenesis: A Model of Oral Squamous Cell Carcinoma

Martinez, CAR (reprint author), Univ Talca, Edificio Dept Ciencias Basicas Biomed, Ave Lircay S-N,Oficina 1, Talca, Chile.The experimental oral carcinogenesis induced by the chemical 4-nitroquinoline 1-oxide (4NQO) is one of the most frequent in the study of squamous cell carcinoma of the oral cavity (CCEC). The clear advantage is that the model is very similar to the physiological process of malignancy. The model has clear benefits by and is suitable for applications in therapeutic research