Salmonella enterica serotype typhi with nonclassical quinolone resistance phenotype
- Accou-Demartin, Marie
- Gaborieau, Valérie
- Song, Yajun
- Roumagnac, Philippe
- Marchou, Bruno
- Achtman, Mark
- Weill, François-Xavier
Publication date
January 2011
DOI Publisher
Centers for Disease Control and Prevention (CDC)Abstract
We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure. (Résumé d'auteur
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