Ebola Virus Disease in Children, Sierra Leone, 2014-2015.
- Fitzgerald, F
- Naveed, A
- Wing, K
- Gbessay, M
- Ross, JCG
- Checchi, F
- Youkee, D
- Jalloh, MB
- Baion, D
- Mustapha, A
- Jah, H
- Lako, S
- Oza, S
- Boufkhed, S
- Feury, R
- Bielicki, JA
- Gibb, DM
- Klein, N
- Sahr, F
- Yeung, S
DOIAbstract
Little is known about potentially modifiable factors in Ebola virus disease in children. We undertook a retrospective cohort study of children <13 years old admitted to 11 Ebola holding units in the Western Area, Sierra Leone, during 2014-2015 to identify factors affecting outcome. Primary outcome was death or discharge after transfer to Ebola treatment centers. All 309 Ebola virus-positive children 2 days-12 years old were included; outcomes were available for 282 (91%). Case-fatality was 57%, and 55% of deaths occurred in Ebola holding units. Blood test results showed hypoglycemia and hepatic/renal dysfunction. Death occurred swiftly (median 3 days after admission) and was associated with younger age and diarrhea. Despite triangulation of...
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