Pyrazinamide (PZA) is a key antituberculosis drug, yet no rapid susceptibility test is commercially available. PZA drug susceptibility testing (DST) was performed directly on sputum samples from 327 patients and compared with the indirect method by using the Bactec MGIT 960 system in the context of patient screening for participation in a drug trial. Compared to standard indirect PZA DST, direct DST was successful in only 59% of cases, but results obtained were highly accurate and available faster. Agreement between the direct and indirect methods varied from 90 to 100% in each laboratory. The median times for obtaining PZA results from the time when the specimen was collected ranged from 11 to 16 days for the direct test and 18 to 95 days ...
The primary platform used for pyrazinamide (PZA) susceptibility testing of Mycobacterium tuberculosi...
Item does not contain fulltextPyrazinamide is important in the treatment of tuberculosis. Unfortunat...
Objectives: The resazurin microtitre plate assay (REMA) was evaluated to determine the susceptibilit...
CITATION: Demers, A.-M. et al. 2016. Direct susceptibility testing of Mycobacterium tuberculosis for...
Conventional indirect drug susceptibility testing ofMycobacterium tuberculosiswith liquid medium is ...
Pyrazinamide (PZA) is considered the pivot drug in all tuberculosis treatment regimens due to its pa...
The susceptibility of 211 clinical isolates ofMycobacterium tuberculosis complex (201M. tuberculosis...
Conventional culture-based drug susceptibility testing (DST) of Mycobacterium tuberculosis to pyrazi...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
The aim of this study was to perform pyrazinamide (PZA) susceptibility testing of M. tuberculosis by...
BACKGROUND: Pyrazinamide (PZA) is a key drug in the treatment of tuberculosis (TB), including multid...
Pyrazinamide (PZA) is a potent first-line agent for the treatment of tuberculosis (TB) with activity...
The primary platform used for pyrazinamide (PZA) susceptibility testing of Mycobacterium tuberculosi...
Item does not contain fulltextPyrazinamide is important in the treatment of tuberculosis. Unfortunat...
Objectives: The resazurin microtitre plate assay (REMA) was evaluated to determine the susceptibilit...
CITATION: Demers, A.-M. et al. 2016. Direct susceptibility testing of Mycobacterium tuberculosis for...
Conventional indirect drug susceptibility testing ofMycobacterium tuberculosiswith liquid medium is ...
Pyrazinamide (PZA) is considered the pivot drug in all tuberculosis treatment regimens due to its pa...
The susceptibility of 211 clinical isolates ofMycobacterium tuberculosis complex (201M. tuberculosis...
Conventional culture-based drug susceptibility testing (DST) of Mycobacterium tuberculosis to pyrazi...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tu...
The aim of this study was to perform pyrazinamide (PZA) susceptibility testing of M. tuberculosis by...
BACKGROUND: Pyrazinamide (PZA) is a key drug in the treatment of tuberculosis (TB), including multid...
Pyrazinamide (PZA) is a potent first-line agent for the treatment of tuberculosis (TB) with activity...
The primary platform used for pyrazinamide (PZA) susceptibility testing of Mycobacterium tuberculosi...
Item does not contain fulltextPyrazinamide is important in the treatment of tuberculosis. Unfortunat...
Objectives: The resazurin microtitre plate assay (REMA) was evaluated to determine the susceptibilit...