Impaired Insulin sensitivity and Insulin secretion in Haemodialysis patients with and without Secondary Hyperparathyroidism

Rasic-Milutinovic, Zorica
Perunicic-Pekovic, Gordana
Pljesa, Steva
Komadina, Ljiljana
Gluvic, Zoran M.
Milic, Natasa

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Publication date

January 2004

Publisher

Malta Medical Journal

Language

English

Abstract

The aim of our study was to investigate insulin sensitivity and beta cell function in hemodialysis (HD) patients without diabetes. We hypothesized that parathyroid gland function was a determinant of insulin sensitivity and/or beta cell function. The study was a randomized, cross-sectional one and patients were divided into two groups (total 27 patients), Gp.1 being those with relative hypoparathyroidism (iPTH<200 pg/ml) 9 (33.3%), Gp.2 those with hyperparathyroidism (iPTH200 pg/ml) 18 (66.6%) with Gp.3 (consisting of 43 healthy subjects acting as controls). Insulin resistance and insulin secretion were calculated from fasting serum insulin and glucose concentrations by the Homeostatic Model Assessment score (HOMA IR and HOMA BETA). The...

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Impaired Insulin sensitivity and Insulin secretion in Haemodialysis patients with and without Secondary Hyperparathyroidism

Abstract

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Impaired Insulin sensitivity and Insulin secretion in Haemodialysis patients with and without Secondary Hyperparathyroidism

Abstract

Extracted data

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