Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes ticks, is the causative agent of Lyme disease. Serum-resistant B. burgdorferi strains cause a chronic, multisystemic form of the disease and bind complement factor H (FH) and FH-like protein 1 (FHL-1) on the spirochete surface. Here we report the atomic structure for the key FHL-1- and FH-binding protein BbCRASP-1 and reveal a homodimer that presents a novel target for drug design
Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved stra...
Borrelia burgdorferi is a spirochete responsible for Lyme disease, the most commonly occurring vecto...
Borrelia burgdorferi sensu lato (Bbsl), the causative agent of Lyme disease, establishes an initial ...
Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes tick...
Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes tick...
Borrelia burgdorferi, a spirochaete transmitted to human hosts during feeding of infected Ixodes tic...
Borrelia burgdorferi exploits multiple strategies to evade host immune responses. One central immune...
Borrelia burgdorferi exploits multiple strategies to evade host immune responses. One central immune...
The etiologic agent of Lyme disease, Borrelia burgdorferi, is capable of circumventing the immune de...
Borrelia burgdorferi has evolved many mechanisms of evading the different immune systems across its ...
Borrelia burgdorferi is the causative agent of Lyme disease and is found in two different types of h...
Tick-borne relapsing fever in North America is primarily caused by the spirochete Borrelia hermsii. ...
Complement regulator-acquiring surface protein 1 (CRASP-1) is the dominant factor-H-like protein 1 (...
The complement regulator-acquiring surface protein (CRASP)-1 is a member of the paralogous gene fami...
Borrelia burgdorferi is the causative agent of Lyme disease and is found in two different types of h...
Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved stra...
Borrelia burgdorferi is a spirochete responsible for Lyme disease, the most commonly occurring vecto...
Borrelia burgdorferi sensu lato (Bbsl), the causative agent of Lyme disease, establishes an initial ...
Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes tick...
Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes tick...
Borrelia burgdorferi, a spirochaete transmitted to human hosts during feeding of infected Ixodes tic...
Borrelia burgdorferi exploits multiple strategies to evade host immune responses. One central immune...
Borrelia burgdorferi exploits multiple strategies to evade host immune responses. One central immune...
The etiologic agent of Lyme disease, Borrelia burgdorferi, is capable of circumventing the immune de...
Borrelia burgdorferi has evolved many mechanisms of evading the different immune systems across its ...
Borrelia burgdorferi is the causative agent of Lyme disease and is found in two different types of h...
Tick-borne relapsing fever in North America is primarily caused by the spirochete Borrelia hermsii. ...
Complement regulator-acquiring surface protein 1 (CRASP-1) is the dominant factor-H-like protein 1 (...
The complement regulator-acquiring surface protein (CRASP)-1 is a member of the paralogous gene fami...
Borrelia burgdorferi is the causative agent of Lyme disease and is found in two different types of h...
Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved stra...
Borrelia burgdorferi is a spirochete responsible for Lyme disease, the most commonly occurring vecto...
Borrelia burgdorferi sensu lato (Bbsl), the causative agent of Lyme disease, establishes an initial ...