Vascular and lymphatic malformations represent a challenge for clinicians. The identi cation of inherited and somatic mutations in important signaling pathways, including the PI3K (phosphoinositide 3-kinase)/AKT (protein kinase B)/mTOR (mammalian target of rapamycin), RAS (rat sarcoma)/RAF (rapidly accelerated brosarcoma)/MEK (mitogen-activated protein kinase kinase)/ERK (extracellular signal-regulated kinases), HGF (hepatocyte growth factor)/c-Met (hepatocyte growth factor receptor), and VEGF (vascular endothelial growth factor) A/VEGFR (vascular endothelial growth factor receptor) 2 cascades has led to the evaluation of tailored strategies with preexisting cancer drugs that interfere with these signaling pathways. The era of theranostics ...
International audienceVascular malformations are poorly recognized constitutional anomalies which ar...
Venous malformations (VMs) are painful and deforming vascular lesions composed of dilated vascular c...
Sporadic vascular malformations (VMs) are a large group of disorders of the blood and lymphatic vess...
Vascular malformations are subdivided into capillary, lymphatic, venous, arteriovenous, and mixed ma...
Vascular anomalies are separated into vascular tumours and vascular malformations. Vascu- lar malfor...
Vascular malformations are inborn errors of vascular morphogenesis and consist of localized networks...
The detection of somatic, activating genetic mutations to underlie development of vascular tumors an...
Vascular anomalies arise as a consequence of improper development and maintenance of the vasculature...
Abstract Vascular anomalies are localized defects of morphogenesis that can affect lymphatic and bl...
Vascular anomalies are developmental defects of the vasculature and encompass a variety of disorders...
Vascular Anomalies are a heterogenous group of vascular lesions that can be divided, according to th...
Lymphatic malformations (LMs) are debilitating vascular anomalies presenting with large cysts (macro...
Vascular Anomalies are a heterogenous group of vascular lesions that can be divided, according to th...
Vascular anomalies are a heterogenous group of vascular lesions that can be divided, according to th...
Lymphatic anomalies include a variety of developmental and/or functional defects affecting the lymph...
International audienceVascular malformations are poorly recognized constitutional anomalies which ar...
Venous malformations (VMs) are painful and deforming vascular lesions composed of dilated vascular c...
Sporadic vascular malformations (VMs) are a large group of disorders of the blood and lymphatic vess...
Vascular malformations are subdivided into capillary, lymphatic, venous, arteriovenous, and mixed ma...
Vascular anomalies are separated into vascular tumours and vascular malformations. Vascu- lar malfor...
Vascular malformations are inborn errors of vascular morphogenesis and consist of localized networks...
The detection of somatic, activating genetic mutations to underlie development of vascular tumors an...
Vascular anomalies arise as a consequence of improper development and maintenance of the vasculature...
Abstract Vascular anomalies are localized defects of morphogenesis that can affect lymphatic and bl...
Vascular anomalies are developmental defects of the vasculature and encompass a variety of disorders...
Vascular Anomalies are a heterogenous group of vascular lesions that can be divided, according to th...
Lymphatic malformations (LMs) are debilitating vascular anomalies presenting with large cysts (macro...
Vascular Anomalies are a heterogenous group of vascular lesions that can be divided, according to th...
Vascular anomalies are a heterogenous group of vascular lesions that can be divided, according to th...
Lymphatic anomalies include a variety of developmental and/or functional defects affecting the lymph...
International audienceVascular malformations are poorly recognized constitutional anomalies which ar...
Venous malformations (VMs) are painful and deforming vascular lesions composed of dilated vascular c...
Sporadic vascular malformations (VMs) are a large group of disorders of the blood and lymphatic vess...
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