HEALTHCARE-ASSOCIATED INFECTIONS IN PAEDIATRIC AND NEONATAL INTENSIVE CARE UNITS: IMPACT OF UNDERLYING RISK FACTORS AND ANTIMICROBIAL RESISTANCE ON 30-DAY CASE-FATALITY

Sharland, M
Folgori, L
Bernaschi, P
Piga, S
Carletti, M
Pirrone Cunha, F
Lara, PHR
Cafeiro de Castro Peixoto, N
Gomes Alves Guimares, B
da Silva, ARA
Atti, MCD

Publication date

November 2016

Publisher

Cambridge University Press (CUP)

Abstract

Objectives. Our aims were (i) to describe trends in the epidemiology of Healthcare-associated Infections (HAIs) in paediatric/neonatal ICUs and (ii) to evaluate risk factors and impact of Multidrug-Resistance (MDR) in children admitted to ICUs. Design. Multicentre, retrospective, cohort study with a nested case-control study conducted between January 2010 and December 2014. Setting. Three tertiary-care paediatric hospitals in Italy and Brazil with a total of 97 ICU beds. Patients. Inclusion criteria were (i) admission to ICU during the study period (ii) age at onset <18 years and (iii) microbiologically-confirmed HAI. Results. 538 HAIs in 454 children were included. 93.3% of patients had comorbidities. Bloodstream infec...

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HEALTHCARE-ASSOCIATED INFECTIONS IN PAEDIATRIC AND NEONATAL INTENSIVE CARE UNITS: IMPACT OF UNDERLYING RISK FACTORS AND ANTIMICROBIAL RESISTANCE ON 30-DAY CASE-FATALITY

Abstract

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HEALTHCARE-ASSOCIATED INFECTIONS IN PAEDIATRIC AND NEONATAL INTENSIVE CARE UNITS: IMPACT OF UNDERLYING RISK FACTORS AND ANTIMICROBIAL RESISTANCE ON 30-DAY CASE-FATALITY

Abstract

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