Xanthone derivatives have shown promising antitumor properties, and 1-carbaldehyde-3,4-dimethoxyxanthone (1) has recently emerged as a potent tumor cell growth inhibitor. In this study, its effect was evaluated (MTT viability assay) against a new panel of cancer cells, namely cervical cancer (HeLa), androgen-sensitive (LNCaP) and androgen-independent (PC-3) prostate cancer, and nonsolid tumor derived cancer (Jurkat) cell lines. The effect of xanthone 1 on macrophage functions was also evaluated. The effect of xanthone 1-conditioned THP-1 human macrophage supernatants on the metabolic viability of cervical and prostate cancer cell lines was determined along with its interference with cytokine expression characteristic of M1 profile (IL-1 ≤ β...
Glutathione transferases (GSTs) are cell detoxifiers involved in multiple drug resistance (MDR), ham...
Dandan Gao,1 Zhimin Guo,1 Jiabin Wang,2 Gaofeng Hu,1 Yuqiao Su,3 Lijun Chen,1 Qianwen Lv,1 Huimei Yu...
Our previous work has described a library of thioxanthones designed to have dual activity as P-glyco...
Xanthone derivatives have shown promising antitumor properties, and 1-carbaldehyde-3,4- dimethoxyxa...
Xanthones have been suggested as prospective candidates for cancer treatment. 1,2- dihydroxyxanthon...
Breast cancer is the most frequently diagnosed cancer in women worldwide.A treatment regime, both ef...
The chemiluminescence of stimulated cells with phorbol myristate acetate and the production of nitr...
Our previous work has described a library of thioxanthones designed to have dual activity as P-glyco...
Natural xanthones are a large group of compounds from which promising anticancer properties could be...
Colorectal cancer currently occupies the third position of globally cancer morbidity and is the seco...
Colorectal carcinoma (CRC) is a kind of malignant tumor closely related to ulcerative colitis. Xanth...
Xanthones bearing different functionalities, namely 1-hydroxyxanthone (1), 3-hydroxyxanthone (2), 1,...
Xanthones bearing different functionalities, namely 1-hydroxyxanthone (1), 3-hydroxyxanthone (2), 1,...
The annual number of cancer deaths continues increasing every day; thus, it is urgent to search for ...
Nowadays, cancer is one of the most fatal diseases in developed and developing countries. Therefore,...
Glutathione transferases (GSTs) are cell detoxifiers involved in multiple drug resistance (MDR), ham...
Dandan Gao,1 Zhimin Guo,1 Jiabin Wang,2 Gaofeng Hu,1 Yuqiao Su,3 Lijun Chen,1 Qianwen Lv,1 Huimei Yu...
Our previous work has described a library of thioxanthones designed to have dual activity as P-glyco...
Xanthone derivatives have shown promising antitumor properties, and 1-carbaldehyde-3,4- dimethoxyxa...
Xanthones have been suggested as prospective candidates for cancer treatment. 1,2- dihydroxyxanthon...
Breast cancer is the most frequently diagnosed cancer in women worldwide.A treatment regime, both ef...
The chemiluminescence of stimulated cells with phorbol myristate acetate and the production of nitr...
Our previous work has described a library of thioxanthones designed to have dual activity as P-glyco...
Natural xanthones are a large group of compounds from which promising anticancer properties could be...
Colorectal cancer currently occupies the third position of globally cancer morbidity and is the seco...
Colorectal carcinoma (CRC) is a kind of malignant tumor closely related to ulcerative colitis. Xanth...
Xanthones bearing different functionalities, namely 1-hydroxyxanthone (1), 3-hydroxyxanthone (2), 1,...
Xanthones bearing different functionalities, namely 1-hydroxyxanthone (1), 3-hydroxyxanthone (2), 1,...
The annual number of cancer deaths continues increasing every day; thus, it is urgent to search for ...
Nowadays, cancer is one of the most fatal diseases in developed and developing countries. Therefore,...
Glutathione transferases (GSTs) are cell detoxifiers involved in multiple drug resistance (MDR), ham...
Dandan Gao,1 Zhimin Guo,1 Jiabin Wang,2 Gaofeng Hu,1 Yuqiao Su,3 Lijun Chen,1 Qianwen Lv,1 Huimei Yu...
Our previous work has described a library of thioxanthones designed to have dual activity as P-glyco...