Background: Eukaryotic cells possess a complex network of RNA machineries which function in RNA-processing and cellular regulation which includes transcription, translation, silencing, editing and epigenetic control. Studies of model organisms have shown that many ncRNAs of the RNA-infrastructure are highly conserved, but little is known from non-model protists. In this study we have conducted a genome-scale survey of medium-length ncRNAs from the protozoan parasites Giardia intestinalis and Trichomonas vaginalis. Results: We have identified the previously ‘missing’ Giardia RNase MRP RNA, which is a key ribozyme involved in pre-rRNA processing. We have also uncovered 18 new H/ACA box snoRNAs, expanding our knowledge of the H/ ACA family of ...
Rnt1p, the only known Saccharomyces cerevisiae RNase III endonuclease, plays important functions in ...
<div><h3>Background</h3><p>5S rRNA is a highly conserved ribosomal component. Eukaryotic 5S rRNA and...
Purpose Ribosome biogenesis is a key process in all living organisms, energetically expensive and ti...
Abstract Background Eukaryotic cells possess a complex network of RNA machineries which function in ...
Non-protein-coding RNAs represent a large proportion of transcribed sequences in eukaryotes. These R...
RNA interference (RNAi) is a set of mechanisms which regulate gene expression in eukaryotes. Key ele...
Many different classes of non-coding (nc)RNAs are found in species throughout the tree of life, each...
Small RNAs (sRNAs), including microRNAs and endogenous siRNAs (endo-siRNAs), regulate most important...
RNAs processing other RNAs is very general in eukaryotes, but is not clear to what extent it is ance...
RNAs processing other RNAs is very general in eukaryotes, but is not clear to what extent it is ance...
<div><p>Trypanosomatids are protozoan parasites and the causative agent of infamous infectious disea...
The discovery of a plethora of small non-coding RNAs (ncRNAs) has fundamentally changed our understa...
RNAs processing other RNAs is very general in eukaryotes, but is not clear to what extent it is ance...
AbstractMicroRNAs (miRNAs) are a class of extensively studied RNAi-associated small RNAs that play a...
Background: 5S rRNA is a highly conserved ribosomal component. Eukaryotic 5S rRNA and its associated...
Rnt1p, the only known Saccharomyces cerevisiae RNase III endonuclease, plays important functions in ...
<div><h3>Background</h3><p>5S rRNA is a highly conserved ribosomal component. Eukaryotic 5S rRNA and...
Purpose Ribosome biogenesis is a key process in all living organisms, energetically expensive and ti...
Abstract Background Eukaryotic cells possess a complex network of RNA machineries which function in ...
Non-protein-coding RNAs represent a large proportion of transcribed sequences in eukaryotes. These R...
RNA interference (RNAi) is a set of mechanisms which regulate gene expression in eukaryotes. Key ele...
Many different classes of non-coding (nc)RNAs are found in species throughout the tree of life, each...
Small RNAs (sRNAs), including microRNAs and endogenous siRNAs (endo-siRNAs), regulate most important...
RNAs processing other RNAs is very general in eukaryotes, but is not clear to what extent it is ance...
RNAs processing other RNAs is very general in eukaryotes, but is not clear to what extent it is ance...
<div><p>Trypanosomatids are protozoan parasites and the causative agent of infamous infectious disea...
The discovery of a plethora of small non-coding RNAs (ncRNAs) has fundamentally changed our understa...
RNAs processing other RNAs is very general in eukaryotes, but is not clear to what extent it is ance...
AbstractMicroRNAs (miRNAs) are a class of extensively studied RNAi-associated small RNAs that play a...
Background: 5S rRNA is a highly conserved ribosomal component. Eukaryotic 5S rRNA and its associated...
Rnt1p, the only known Saccharomyces cerevisiae RNase III endonuclease, plays important functions in ...
<div><h3>Background</h3><p>5S rRNA is a highly conserved ribosomal component. Eukaryotic 5S rRNA and...
Purpose Ribosome biogenesis is a key process in all living organisms, energetically expensive and ti...