This study aimed to evaluate protection induced by the vaccine candidate B. ovis ΔabcBA against experimental challenge with wild type B. ovis in rams. Rams were subcutaneously immunized with B. ovis ΔabcBA encapsulated with sterile alginate or with the non encapsulated vaccine strain. Serum, urine, and semen samples were collected during two months after immunization. The rams were then challenged with wild type B. ovis (ATCC25840), and the results were compared to non immunized and experimentally challenged rams. Immunization, particularly with encapsulated B. ovis ΔabcBA, prevented infection, secretion of wild type B. ovis in the semen and urine, shedding of neutrophils in the semen, and the development of clinical changes,...
Bovine brucellosis is caused by Brucella abortus. The bacterial pathogen causes economic losses beca...
Brucella is a Gram-negative, facultative intracellular bacterium that causes severe disease in both ...
Brucella ovis is a major cause of reproductive failure in sheep, which is associated with epididymit...
This study aimed to evaluate protection induced by the vaccine candidate B. ovis ΔabcBA against...
Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economi...
Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economi...
Sheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species r...
Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economi...
This is an open access article distributed under the terms of the Creative Commons Attribution Licen...
Brucella species are the causative agents of brucellosis, which is regarded as the world's most prev...
Ovine epididymitis, caused by Brucella ovis, can lead to severe economic losses in sheep-producing c...
BACKGROUND/OBJECTIVES:Vaccination is the most important tool for controlling brucellosis, but curren...
We have engineered the polymeric vaccine BLSOmp31 by decorating the highly immunogenic and decameric...
Brucella ovis infection is associated with epididymitis, orchitis and infertility in rams. Most of t...
Brucella ovis is the etiologic agent of ovine brucellosis. The control measures for this disease are...
Bovine brucellosis is caused by Brucella abortus. The bacterial pathogen causes economic losses beca...
Brucella is a Gram-negative, facultative intracellular bacterium that causes severe disease in both ...
Brucella ovis is a major cause of reproductive failure in sheep, which is associated with epididymit...
This study aimed to evaluate protection induced by the vaccine candidate B. ovis ΔabcBA against...
Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economi...
Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economi...
Sheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species r...
Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economi...
This is an open access article distributed under the terms of the Creative Commons Attribution Licen...
Brucella species are the causative agents of brucellosis, which is regarded as the world's most prev...
Ovine epididymitis, caused by Brucella ovis, can lead to severe economic losses in sheep-producing c...
BACKGROUND/OBJECTIVES:Vaccination is the most important tool for controlling brucellosis, but curren...
We have engineered the polymeric vaccine BLSOmp31 by decorating the highly immunogenic and decameric...
Brucella ovis infection is associated with epididymitis, orchitis and infertility in rams. Most of t...
Brucella ovis is the etiologic agent of ovine brucellosis. The control measures for this disease are...
Bovine brucellosis is caused by Brucella abortus. The bacterial pathogen causes economic losses beca...
Brucella is a Gram-negative, facultative intracellular bacterium that causes severe disease in both ...
Brucella ovis is a major cause of reproductive failure in sheep, which is associated with epididymit...