Adulticidal activity of dillapiol and semi-synthetic derivatives of dillapiol against adults of Aedes aegypti (L.) (Culicidae).

Phenylpropanoid(1) dillapiolisolated from the essential oil of leaves of Piper aduncum L. and thirteen semi-synthetic, C3 side-chain modified dillapiol derivatives 2-14 were evaluated for lethality against hemorrhagic dengue fever mosquito vector Aedes aegypti L. First, adult female mosquitoes were exposed to these substances in a contact bioassay carried out in glass bottles at a single surface density (0.57 mg/cm2). Then median lethal concentrations (LC50) and LC90 were determined for active compounds