From rigid to flexible: graphene-based extracellular sensors

Having a chip with a large array of sensitive, fast and linearly responsive, and stable recording sites is a holy grail of biological sensors for the recording of extracellular potentials from electrogenic cells, especially neurons. Such kinds of chips have been and still being fabricated and used. But these chips are mostly based on silicon and silicon technology. The main drawback of these devices is their inflexibility and high Young’s modulus. Therefore, such devices are unusable if one wants to go into flexible in-vivo sensors. Graphene, considering its overall properties [1], seems to be the cornerstone for bringing high tech of microelectronics into flexible shell and into biology. The graphene field effect transistors (GFETs) show great performance in terms of response time (