Add to ORKGThis study describes the synthesis of a new ruthenium nitrosyl complex with the formula [RuCl(2)NO(BPA)] [BPA = (2-hydroxybenzyl)(2-methylpyridyl)amine ion], which was synthesized and characterized by spectroscopy, cyclic voltammetry, X-ray crystallography, and theoretical calculation data. The biological studies of this complex included in vitro cytotoxic assays, which revealed its activity against two different tumor cell lines (HeLa and Tm5), with efficacy comparable to that of cisplatin, a metal-based drug that is administered in clinical treatment. The in vivo studies showed that [RuCl2NO(BPA)] is effective in reducing tumor mass. Also, our results suggest that the mechanism of action of [RuCl(2)NO(BPA)] includes binding to DNA, causin...
Two new Ru(II) complexes, [Ru(bpy)2(FAMP)](ClO4)2 1 and 2, are synthesized and characterized by elem...
Despite significant advancements in cancer treatment, there is a constant need for new and effective...
The reactions of [Ru(NO)Cl<sub>5</sub>]<sup>2–</sup> with glycine (Gly), l-alanine (l-Ala), l-vali...
This study describes the synthesis of a new ruthenium nitrosyl complex with the formula [RuCl(2)NO(B...
The behavior of nitric oxide (NO) in biological systems has been under intense investigation in rece...
Ruthenium compounds of the type trans-[Ru(NO)(NH3)(4)(L)] X-3, L = N-heterocyclic ligands, P(OEt)(3)...
Ruthenium compounds of the type trans-[Ru(NO)(NH3)(4)(L)] X-3, L = N-heterocyclic ligands, P(OEt)(3)...
International audienceThe reactions of [Ru(NO)Cl5]2– with glycine (Gly), l-alanine (l-Ala), l-valine...
AbstractWe report on the synthesis of novel Ru(II) compounds (Ru-1 to Ru-8) bearing R-pdc, 4-Cl-pbin...
*S Supporting Information ABSTRACT: The reactions of [Ru(NO)Cl5] 2 − with glycine (Gly), L-alanine (...
The complex [Ru(bpy)z(NO)(N02)](PF6)2 was investigated as a potential anti tumor drug option. The n...
Since the discovery that nitric oxide (NO) is a physiologically relevant molecule, there has been gr...
Seit Cisplatin entdeckt wurde, sind Platinum(II) Komplexe ein integraler Bestandteil der anti-Krebs ...
A series of dinuclear ruthenium(II) complexes that contain labile chlorido ligands, [{Ru(tpy)Cl}2{mu...
Two new Ru(II) complexes, [Ru(bpy)2(FAMP)](ClO4)2 1 and 2, are synthesized and characterized by elem...
Two new Ru(II) complexes, [Ru(bpy)2(FAMP)](ClO4)2 1 and 2, are synthesized and characterized by elem...
Despite significant advancements in cancer treatment, there is a constant need for new and effective...
The reactions of [Ru(NO)Cl<sub>5</sub>]<sup>2–</sup> with glycine (Gly), l-alanine (l-Ala), l-vali...
This study describes the synthesis of a new ruthenium nitrosyl complex with the formula [RuCl(2)NO(B...
The behavior of nitric oxide (NO) in biological systems has been under intense investigation in rece...
Ruthenium compounds of the type trans-[Ru(NO)(NH3)(4)(L)] X-3, L = N-heterocyclic ligands, P(OEt)(3)...
Ruthenium compounds of the type trans-[Ru(NO)(NH3)(4)(L)] X-3, L = N-heterocyclic ligands, P(OEt)(3)...
International audienceThe reactions of [Ru(NO)Cl5]2– with glycine (Gly), l-alanine (l-Ala), l-valine...
AbstractWe report on the synthesis of novel Ru(II) compounds (Ru-1 to Ru-8) bearing R-pdc, 4-Cl-pbin...
*S Supporting Information ABSTRACT: The reactions of [Ru(NO)Cl5] 2 − with glycine (Gly), L-alanine (...
The complex [Ru(bpy)z(NO)(N02)](PF6)2 was investigated as a potential anti tumor drug option. The n...
Since the discovery that nitric oxide (NO) is a physiologically relevant molecule, there has been gr...
Seit Cisplatin entdeckt wurde, sind Platinum(II) Komplexe ein integraler Bestandteil der anti-Krebs ...
A series of dinuclear ruthenium(II) complexes that contain labile chlorido ligands, [{Ru(tpy)Cl}2{mu...
Two new Ru(II) complexes, [Ru(bpy)2(FAMP)](ClO4)2 1 and 2, are synthesized and characterized by elem...
Two new Ru(II) complexes, [Ru(bpy)2(FAMP)](ClO4)2 1 and 2, are synthesized and characterized by elem...
Despite significant advancements in cancer treatment, there is a constant need for new and effective...
The reactions of [Ru(NO)Cl<sub>5</sub>]<sup>2–</sup> with glycine (Gly), l-alanine (l-Ala), l-vali...