In the present study, we evaluated the role of glutamatergic mechanisms in the retrotrapezoid nucleus (RTN) in changes of splanchnic sympathetic nerve discharge (sSND) and phrenic nerve discharge (PND) elicited by central and peripheral chemoreceptor activation. Mean arterial pressure (MAP), sSND and PND were recorded in urethane-anaesthetized, vagotomized, sino-aortic denervated and artificially ventilated male Wistar rats. Hypercapnia (10% CO(2)) increased MAP by 32 +/- 4 mmHg, sSND by 104 +/- 4% and PND amplitude by 101 +/- 5%. Responses to hypercapnia were reduced after bilateral injection of the NMDA receptor antagonist D,L-2-amino-5-phosphonovalerate (AP-5; 100mm in 50 nl) in the RTN (MAP increased by 16 +/- 3 mmHg, sSNDby 82 +/- 3% a...
The role of (+/-)-α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA)-kainate and N-methyl-...
The involvement of glutamatergic neurotransmission in the rostral ventrolateral medulla/Bötzinger/pr...
Moraes DJ, Zoccal DB, Machado BH. Sympathoexcitation during chemoreflex active expiration is mediate...
In the present study, we evaluated the role of glutamatergic mechanisms in the retrotrapezoid nucleu...
A rise in arterial PCO(2) stimulates breathing and sympathetic activity to the heart and blood vesse...
A rise in arterial PCO2 stimulates breathing and sympathetic activity to the heart and blood vessels...
The present study explores how elevations in brain P-CO2 increase the sympathetic nerve discharge (S...
Moraes DJ, Dias MB, Cavalcanti-Kwiatkoski R, Machado BH, Zoccal DB. Contribution of retrotrapezoid n...
Moraes DJ, Dias MB, Cavalcanti-Kwiatkoski R, Machado BH, Zoccal DB. Contribution of retrotrapezoid n...
Peripheral chemoreflex activation in awake rats or in the working heart-brainstem preparation (WHBP)...
Peripheral chemoreflex activation in awake rats or in the working heart-brainstem preparation (WHBP)...
The rat retrotrapezoid nucleus (RTN) contains pH-sensitive neurons that are putative central chemore...
AbstractPeripheral chemoreflex activation with potassium cyanide (KCN) in awake rats, or in the work...
The caudal pressor area (CPA) is a brainstem area located close to the spinal cord. The activation o...
Peripheral chemoreflex activation with potassium cyanide (KCN) in awake rats or in the working heart...
The role of (+/-)-α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA)-kainate and N-methyl-...
The involvement of glutamatergic neurotransmission in the rostral ventrolateral medulla/Bötzinger/pr...
Moraes DJ, Zoccal DB, Machado BH. Sympathoexcitation during chemoreflex active expiration is mediate...
In the present study, we evaluated the role of glutamatergic mechanisms in the retrotrapezoid nucleu...
A rise in arterial PCO(2) stimulates breathing and sympathetic activity to the heart and blood vesse...
A rise in arterial PCO2 stimulates breathing and sympathetic activity to the heart and blood vessels...
The present study explores how elevations in brain P-CO2 increase the sympathetic nerve discharge (S...
Moraes DJ, Dias MB, Cavalcanti-Kwiatkoski R, Machado BH, Zoccal DB. Contribution of retrotrapezoid n...
Moraes DJ, Dias MB, Cavalcanti-Kwiatkoski R, Machado BH, Zoccal DB. Contribution of retrotrapezoid n...
Peripheral chemoreflex activation in awake rats or in the working heart-brainstem preparation (WHBP)...
Peripheral chemoreflex activation in awake rats or in the working heart-brainstem preparation (WHBP)...
The rat retrotrapezoid nucleus (RTN) contains pH-sensitive neurons that are putative central chemore...
AbstractPeripheral chemoreflex activation with potassium cyanide (KCN) in awake rats, or in the work...
The caudal pressor area (CPA) is a brainstem area located close to the spinal cord. The activation o...
Peripheral chemoreflex activation with potassium cyanide (KCN) in awake rats or in the working heart...
The role of (+/-)-α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA)-kainate and N-methyl-...
The involvement of glutamatergic neurotransmission in the rostral ventrolateral medulla/Bötzinger/pr...
Moraes DJ, Zoccal DB, Machado BH. Sympathoexcitation during chemoreflex active expiration is mediate...