The objective of the present study was to evaluate sphingolipid levels (sphingosine-So and sphinganine-Sa) and to compare the Sa/So ratio in liver, serum and urine of Wistar rats after prolonged administration (21 days) of fumonisin B(1) (FB(1)). In parallel, the kinetics of sphingolipid elimination in urine was studied in animals receiving a single dose of FB(1). Prolonged exposure to FB(1) caused an increase in Sa levels in urine, serum and liver. The most marked effect on sphingolipid biosynthesis was observed in animals treated with the highest dose of FB(1). Animals receiving a single dose of FB(1) presented variations in Sa and So levels and in the Sa/So ratio
Fumonisins (FB) are mycotoxins known to exert most of their toxicity by blocking ceramide synthase, ...
The effects of prolonged oral administration (21 days) of fumonisin B(1) (FB(1)) and aflatoxin B(1) ...
The mycotoxin fumonisin B1 (FB1) is a frequent contaminant of feed. It causes a disruption of sphing...
The objective of the present study was to evaluate sphingolipid levels (sphingosine-So and sphingani...
The objective of the present study was to evaluate sphingolipid levels (sphingosine-So and sphingani...
This is the first report of sphinganine (Sa) and sphingosine (So) levels determined in serum and uri...
Fumonisins (FBs) are mycotoxins in maize and are inhibitors of ceramide synthase (CS), the most like...
ArticleThe disruption in sphinganine (Sa) and sphingosine (So) concentrations in plasma and urine of...
none[Synopsis] The increase of sphinganine/sphingosine (SA/SO) ratio in biological fluids and tissue...
Due to its structural similarity with sphingosine, fumonisin B, (FBI) inhibits ceramide synthase (a ...
ArticleThe modulating role of fumonisin B1 (FB1) on lipid biosynthesis was evaluated in a shortterm ...
he fumonisins and toxins produced by Alternaria alternata f. sp. lycopersici (AAL toxins) are struct...
Toxicokinetics and the toxicological effects of culture material containing fumonisin B(1) (FB(1)) w...
It is known that exposure to mycotoxin fumonisin B1 (FB1) causes apoptosis and increases lipid perox...
ArticleIn order to investigate the role of sphingolipid disruption in the cancer promoting potential...
Fumonisins (FB) are mycotoxins known to exert most of their toxicity by blocking ceramide synthase, ...
The effects of prolonged oral administration (21 days) of fumonisin B(1) (FB(1)) and aflatoxin B(1) ...
The mycotoxin fumonisin B1 (FB1) is a frequent contaminant of feed. It causes a disruption of sphing...
The objective of the present study was to evaluate sphingolipid levels (sphingosine-So and sphingani...
The objective of the present study was to evaluate sphingolipid levels (sphingosine-So and sphingani...
This is the first report of sphinganine (Sa) and sphingosine (So) levels determined in serum and uri...
Fumonisins (FBs) are mycotoxins in maize and are inhibitors of ceramide synthase (CS), the most like...
ArticleThe disruption in sphinganine (Sa) and sphingosine (So) concentrations in plasma and urine of...
none[Synopsis] The increase of sphinganine/sphingosine (SA/SO) ratio in biological fluids and tissue...
Due to its structural similarity with sphingosine, fumonisin B, (FBI) inhibits ceramide synthase (a ...
ArticleThe modulating role of fumonisin B1 (FB1) on lipid biosynthesis was evaluated in a shortterm ...
he fumonisins and toxins produced by Alternaria alternata f. sp. lycopersici (AAL toxins) are struct...
Toxicokinetics and the toxicological effects of culture material containing fumonisin B(1) (FB(1)) w...
It is known that exposure to mycotoxin fumonisin B1 (FB1) causes apoptosis and increases lipid perox...
ArticleIn order to investigate the role of sphingolipid disruption in the cancer promoting potential...
Fumonisins (FB) are mycotoxins known to exert most of their toxicity by blocking ceramide synthase, ...
The effects of prolonged oral administration (21 days) of fumonisin B(1) (FB(1)) and aflatoxin B(1) ...
The mycotoxin fumonisin B1 (FB1) is a frequent contaminant of feed. It causes a disruption of sphing...