Repercussions of premature rupture of fetal membranes on neonatal morbidity and mortality

O objetivo foi analisar os fatores associados ao ??bito e sobrevida com seq??ela em neonatos egressos de gesta????es que cursaram com amniorrexe prematura. Estudo observacional do tipo coorte hist??rica analisou prontu??rios de pacientes que evolu??ram com quadro de amniorrexe prematura less than 34 semanas de gesta????o. As vari??veis foram cotejadas com os desfechos ??bito neonatal e sobrevida com seq??ela. Em ambos os grupos os dados foram submetidos ?? an??lise bivariada, sendo os valores que exibem signific??ncia estat??stica submetidos ?? regress??o log??stica. No modelo multivariado final em rela????o ao ??bito fetal tiveram signific??ncia estat??stica: corioamnionite; ??ndice de Apgar less than 5 no 5?? minuto; peso ao nascimento less than 1.000g; e reanima????o cardiopulmonar. Quanto ?? presen??a de seq??ela entre os sobreviventes destacam se: a coloniza????o cervical; persist??ncia do canal arterial; ??ndice de Apgar less than 5 no 5?? minuto; e peso ao nascimento less than 1.000g. Processos infecciosos, extremo baixo peso ao nascer e asfixia periparto s??o as principais vari??veis ligadas aos desfechos estudados entre neonatos egressos de gesta????es que cursaram com amniorrexe prematura.The objective of this study was to analyze factors associated with death and survival with sequelae in neonates after premature rupture of fetal membranes (PROM). An observational historical cohort study analyzed charts of patients with PROM at less than 34 weeks gestation. The variables were compared with neonatal death and survival with sequelae as the outcomes. In both groups, the data were submitted to bivariate analysis, and the variables showing significance were submitted to logistic regression. The final multivariate model for fetal death showed statistical significance for the following: chorioamnionitis; 5-minute Apgar score less than 5; birth weight less than 1,000g; and cardiopulmonary resuscitation. Survival with sequela was associated with: cervical colonization; patent ductus arteriosus; 5-minute Apgar score less than 5; and birth weight less than 1,000g. Infections, very low birth weight, and peripartum asphyxia were the principal variables associated with the target outcomes among newborns from gestations involving PROM