The thesis deals with the analysis of possibilities for use of III. and IV. generation of nuclear reactors for the Czech Republic. Introduction deals with basic principles of nuclear energetics and fuel cycle which is closely associated with the issue and its development and application in practice will have a significant effect both for choice of future types of nuclear reactors of IV. generation and the matter of settlement with spent nuclear fuel. In other parts the thesis deals with the present state of nuclear energetics in the Czech Republic, compares concrete chosen types of nuclear power plants of III. generation and generally describes nuclear reactors and power plants of IV. generation. Final part of the work is focused on questio...