Master thesis deals with designing of air-conditioning system into newly reconstructed high-rise building of Faculty of Mechanical Engineering Brno University of Technology. Reconstruction of a building results in change of thermo-technical parameters which impacts dimensioning of air condition system. Designing air-conditioning system depends on heat loss and heat gain calculation and also on consequential psychometrical calculations. The size of air conditioning equipment which provides required internal microclimate will be determined from the calculation results. Currently there is Detail design elaborated including technical report and material specification