Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage
- Anderson, Craig S.
- Heeley, Emma
- Huang, Yining
- Wang, Jiguang
- Stapf, Christian
- Delcourt, Candice
- Lindley, Richard
- Robinson, Thompson
- Lavados Germain, Pablo Manuel
- Neal, Bruce
- Hata, Jun
- Arima, Hisatomi
- Parsons, Mark
- Li, Yuechun
- Wang, Jinchao
- Heritier, Stephane
- Qiang, Li
- Woodward, Mark
- Simes, John
- Davis, Stephen M.
- Chalmers Barraza, John
DOIAbstract
Artículo de publicación ISIBackground Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. Methods We randomly assigned 2839 patients who had had a spontaneous intracerebral hemorrhage within the previous 6 hours and who had elevated systolic blood pressure to receive intensive treatment to lower their blood pressure (with a target systolic level of <140 mm Hg within 1 hour) or guideline-recommended treatment (with a target systolic level of <180 mm Hg) with the use of agents of the physician’s choosing. The primary outcome was death or major disability, which was defined as a score of 3 to 6 on the modified Rankin scale (in which a score of 0 indicates...
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