Integrated Pressurized Solvent Extraction-Cleanup for the Rapid Determination of Polychlorinated Biphenyls in Meat Samples

Artículo de publicación ISIA rapid and efficient method based on the integration of pressurized solvent extraction (PSE) with solid phase extraction (SPE) cleanup and gas chromatography system with electron capture detection (GC-ECD) has been developed for determination of polychlorinated biphenyls (PCBs). Six indicators and twelve dioxin-like PCBs were selected as analytes. This method is based on the integration of solvent extraction and cleanup processes inside a pressurized stainless steel cell. The optimum extraction conditions were 6 min of extraction at 70 °C and two cycles of extraction using hexane/methylene chloride (1:1, v/v) as the extraction solvent. Silica gel acidified with sulfuric acid was used for integrated cleanup of the organic extract. This method allows a significant reduction in extraction time and solvent consumption. Repeatability, expressed as the relative standard deviation, ranged from 3 to 6%, and recoveries for concentration of 20 ng g−1 was ranged between 71 to 104% .The limit of detection and quantification ranged from 0.03 to 0.29 ng g−1 and 0.1 to 0.97 ng g−1 respectively. The linear range was between 5 and 100 ng g−1 . Finally this new method was applied to samples of chicken and pork