In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasites, and particularly against African Trypanosomiasis, whose etiological agent is Trypanosoma brucei, organoruthenium compounds with bioactive nitrofuran containing thiosemicarbazones (L) as co-ligands were obtained. Four ruthenium(II) complexes with the formula [Ru(2)(p-cymene)(2)(L)(2)]X(2), where X = Cl or PF(6), were synthesized and the crystal structures of two of them were solved by X-ray diffraction methods. Two of the complexes show significant in vitro growth inhibition activity against Trypanosoma brucei brucei and are highly selective towards trypanosomal cells with respect to mammalian cells (J774 murine macrophages). These promis...
A series of ferrocenyl- and aryl-functionalised organosilane thiosemicarbazone compounds was obtaine...
We present the preliminary results of a study of two novel thiosemicarbazones (TSCs) and theirruthen...
A series of aryl-functionalized and ferrocenyl monothiosemicarbazone compounds (L1-L4) were synthesi...
In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasi...
In the search of new therapeutic tools for the treatment of American Trypanosomiasis, the largest pa...
In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasi...
Artículo de publicación ISIIn the search for new metal-based drugs against diseases produced by try...
Artículo de publicación ISISearching for new prospective antitrypanosomal agents, three novel Ru(II)...
Rhenium and ruthenium complexes of the type [(ReOCl2)-O-V(PPh3)L] and [(RuC2)-C-II(DMSO)(2)L], where...
Complexes [RuCl(H4NO(2)Fo4M)(bipy)(dppb)]PF(6) (1), [RuCl(H4NO(2)Fo4M)(Mebipy)(dppb)]PF(6) (2), [RuC...
Artículo de publicación ISIParasitic illnesses are major causes of human disease and misery worldwi...
Chagas' disease, considered incurable, is a major third world parasitosis that affects millions of p...
Four new organoruthenium complexes with formula [RuCl(?6-p-cymene)(?-FCZ)]2[Cl]2 (1), [RuCl(FCZ)(?6-...
Nine organoruthenium complexes with azole antifungal agents (L) clotrimazole (ctz), tioconazole (tcz...
Human African trypanosomiasis (sleeping sickness) and leishmaniasis are prevalent zoonotic diseases ...
A series of ferrocenyl- and aryl-functionalised organosilane thiosemicarbazone compounds was obtaine...
We present the preliminary results of a study of two novel thiosemicarbazones (TSCs) and theirruthen...
A series of aryl-functionalized and ferrocenyl monothiosemicarbazone compounds (L1-L4) were synthesi...
In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasi...
In the search of new therapeutic tools for the treatment of American Trypanosomiasis, the largest pa...
In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasi...
Artículo de publicación ISIIn the search for new metal-based drugs against diseases produced by try...
Artículo de publicación ISISearching for new prospective antitrypanosomal agents, three novel Ru(II)...
Rhenium and ruthenium complexes of the type [(ReOCl2)-O-V(PPh3)L] and [(RuC2)-C-II(DMSO)(2)L], where...
Complexes [RuCl(H4NO(2)Fo4M)(bipy)(dppb)]PF(6) (1), [RuCl(H4NO(2)Fo4M)(Mebipy)(dppb)]PF(6) (2), [RuC...
Artículo de publicación ISIParasitic illnesses are major causes of human disease and misery worldwi...
Chagas' disease, considered incurable, is a major third world parasitosis that affects millions of p...
Four new organoruthenium complexes with formula [RuCl(?6-p-cymene)(?-FCZ)]2[Cl]2 (1), [RuCl(FCZ)(?6-...
Nine organoruthenium complexes with azole antifungal agents (L) clotrimazole (ctz), tioconazole (tcz...
Human African trypanosomiasis (sleeping sickness) and leishmaniasis are prevalent zoonotic diseases ...
A series of ferrocenyl- and aryl-functionalised organosilane thiosemicarbazone compounds was obtaine...
We present the preliminary results of a study of two novel thiosemicarbazones (TSCs) and theirruthen...
A series of aryl-functionalized and ferrocenyl monothiosemicarbazone compounds (L1-L4) were synthesi...