Add to ORKGThe present invention relates to certain 4-(substituted aniline)-2-(substituted piperidin-1-yl)pyrimidine- -carboxamide compounds which may be useful in the treatment or prevention of a disease or medical condition mediated through signalling of CaMK1 isoforms. For example, such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers, metabolic diseases including type-2 diabetes, and/or immune-mediated disorders
The invention provides a compound that is an inhibitor of one or both of TBK1 and IKKe, or a down-re...
The Pim proteins (1, 2 and 3) are serine/threonine kinases that have been found to be upregulated in...
The present invention relates to novel heterocyclic derivatives having general formula (I) and thei...
The present invention relates to certain 4-(substituted aniline)-2-(substituted piperidin-1-yl)pyrim...
The invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as prot...
The present invention concerns a compound of formula (I), in particular as LIMK and/or ROCK kinases ...
The invention provides compounds of formula (I) wherein R is −CH3 or −CH2CH3 and pharmaceutically ac...
Protein kinase B (PKB or Akt) is an important component of intracellular signaling pathways regulati...
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases assoc...
The present invention relates to novel piperidine derivatives having better cell growth inhibitory a...
The present invention concern a 2-oxo-1,2-dihydropyridine-3-carboxamide compound of Formula (I) and ...
The present invention relates to 4-pyrimidinylamino-benzenesulfonamide derivatives of general formul...
This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
The present invention concern a 2-oxo-1,2-dihydropyridine-3-carboxamide compound of Formula (I) in t...
The invention provides a compound that is an inhibitor of one or both of TBK1 and IKKe, or a down-re...
The Pim proteins (1, 2 and 3) are serine/threonine kinases that have been found to be upregulated in...
The present invention relates to novel heterocyclic derivatives having general formula (I) and thei...
The present invention relates to certain 4-(substituted aniline)-2-(substituted piperidin-1-yl)pyrim...
The invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as prot...
The present invention concerns a compound of formula (I), in particular as LIMK and/or ROCK kinases ...
The invention provides compounds of formula (I) wherein R is −CH3 or −CH2CH3 and pharmaceutically ac...
Protein kinase B (PKB or Akt) is an important component of intracellular signaling pathways regulati...
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases assoc...
The present invention relates to novel piperidine derivatives having better cell growth inhibitory a...
The present invention concern a 2-oxo-1,2-dihydropyridine-3-carboxamide compound of Formula (I) and ...
The present invention relates to 4-pyrimidinylamino-benzenesulfonamide derivatives of general formul...
This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
The present invention concern a 2-oxo-1,2-dihydropyridine-3-carboxamide compound of Formula (I) in t...
The invention provides a compound that is an inhibitor of one or both of TBK1 and IKKe, or a down-re...
The Pim proteins (1, 2 and 3) are serine/threonine kinases that have been found to be upregulated in...
The present invention relates to novel heterocyclic derivatives having general formula (I) and thei...