Exploring the reactivity and biological effects of heteroleptic N-Heterocyclic carbene gold(I)-Alkynyl complexes
- Oberkofler, Jens
- Aikman, Brech
- Bonsignore, Riccardo
- Pöthig, Alexander
- Platts, James
- Casini, Angela
- Kühn, Fritz E.
DOIAbstract
Two families of heteroleptic N‐heterocyclic carbene gold(I)‐alkynyl complexes have been synthesized and characterized by different methods. Their reactivity with model thiols has been studied by NMR spectroscopy and DFT calculations. Moreover, preliminary studies on the compounds' reactivity with DNA and antiproliferative effects have been conducted
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